[HTML][HTML] Extracellular vesicles from human plasma and serum are carriers of extravesicular cargo—Implications for biomarker discovery

M Palviainen, M Saraswat, Z Varga, D Kitka… - PloS one, 2020 - journals.plos.org
Extracellular vesicles (EVs) in human blood are a potential source of biomarkers. To which
extent anticoagulation affects their concentration, cellular origin and protein composition is …

[HTML][HTML] Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle …

X Zhang, T Takeuchi, A Takeda, H Mochizuki… - PLoS One, 2022 - journals.plos.org
Extracellular vesicles (EVs) have attracted much attention as potential diagnostic biomarkers
for human diseases. Although both plasma and serum are utilized as a source of blood EVs …

[HTML][HTML] Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

N Karimi, A Cvjetkovic, SC Jang, R Crescitelli… - Cellular and molecular …, 2018 - Springer
The isolation of extracellular vesicles (EVs) from blood is of great importance to understand
the biological role of circulating EVs and to develop EVs as biomarkers of disease. Due to …

[HTML][HTML] Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration

N Arraud, R Linares, S Tan, C Gounou… - Journal of Thrombosis …, 2014 - Elsevier
Background Plasma and other body fluids contain membranous extracellular vesicles (EVs),
which are considered to derive from activated or apoptotic cells. EVs participate in …

[HTML][HTML] Removal of platelets from blood plasma to improve the quality of extracellular vesicle research

B Bettin, A Gasecka, B Li, B Dhondt, A Hendrix… - Journal of Thrombosis …, 2022 - Elsevier
Background Blood plasma is commonly used for biomarker research of extracellular
vesicles (EVs). Removing all cells prior to analysis of EVs is essential. Objectives We …

[HTML][HTML] Blood nanoparticles–influence on extracellular vesicle isolation and characterization

M Holcar, M Kandušer, M Lenassi - Frontiers in Pharmacology, 2021 - frontiersin.org
Blood is a rich source of disease biomarkers, which include extracellular vesicles (EVs). EVs
are nanometer-to micrometer-sized spherical particles that are enclosed by a phospholipid …

[HTML][HTML] A size-exclusion-based approach for purifying extracellular vesicles from human plasma

PM Vanderboom, S Dasari, GN Ruegsegger… - Cell reports …, 2021 - cell.com
Extracellular vesicles (EVs) are released into blood from multiple organs and carry
molecular cargo that facilitates inter-organ communication and an integrated response to …

A beginner's guide to study extracellular vesicles in human blood plasma and serum

R Nieuwland, PRM Siljander - Journal of extracellular vesicles, 2024 - Wiley Online Library
Blood is the most commonly used body fluid for obtaining and studying extracellular vesicles
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …

[HTML][HTML] A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum

K Brennan, K Martin, SP FitzGerald, J O'sullivan… - Scientific reports, 2020 - nature.com
Extracellular vesicles (EVs) are nano-sized vesicles containing nucleic acid and protein
cargo that are released from a multitude of cell types and have gained significant interest as …

Isolation and characterization of microvesicles from peripheral blood

K Menck, A Bleckmann, M Schulz, L Ries… - Jove (Journal of …, 2017 - jove.com
The release of extracellular vesicles (EVs) including small endosomal-derived exosomes
(Exos, diameter< 100 nm) and large plasma membrane-derived microvesicles (MVs …