[HTML][HTML] Long-read assembly of major histocompatibility complex and killer cell immunoglobulin-like receptor genome regions in cynomolgus macaque

Q Hu, X Huang, Y Jin, R Zhang, A Zhao, Y Wang… - Biology Direct, 2022 - Springer
Background The major histocompatibility complex (MHC) and the killer cell immunoglobulin-
like receptors (KIR) are key regulators of immune responses. The cynomolgus macaque, an …

Major histocompatibility complex haplotyping and long-amplicon allele discovery in cynomolgus macaques from Chinese breeding facilities

JA Karl, ME Graham, RW Wiseman, KE Heimbruch… - Immunogenetics, 2017 - Springer
Very little is currently known about the major histocompatibility complex (MHC) region of
cynomolgus macaques (Macaca fascicularis; Mafa) from Chinese breeding centers. We …

[HTML][HTML] Dynamic evolution of Mhc haplotypes in cynomolgus macaques of different geographic origins

NG de Groot, N de Groot, AJM de Vos-Rouweler… - Immunogenetics, 2022 - Springer
The major histocompatibility complex (MHC) plays a key role in immune defense, and the
Mhc genes of cynomolgus macaque display a high degree of polymorphism. Based on their …

Complete genomic assembly of Mauritian cynomolgus macaque killer immunoglobulin-like receptor and natural killer group 2 haplotypes

TM Prall, JA Karl, JM Varghese, DA Baker, NR Minor… - bioRxiv, 2023 - biorxiv.org
Mauritian-origin cynomolgus macaques (MCM) serve as a powerful nonhuman primate
model in biomedical research due to their unique genetic homogeneity, which simplifies …

Improved full-length killer cell immunoglobulin-like receptor transcript discovery in Mauritian cynomolgus macaques

TM Prall, ME Graham, JA Karl, RW Wiseman… - Immunogenetics, 2017 - Springer
Killer cell immunoglobulin-like receptors (KIRs) modulate disease progression of pathogens
including HIV, malaria, and hepatitis C. Cynomolgus and rhesus macaques are widely used …

[HTML][HTML] MHC class I allele diversity in cynomolgus macaques of Vietnamese origin

S Huang, X Huang, S Li, M Zhu, M Zhuo - PeerJ, 2019 - peerj.com
Cynomolgus macaques (Macaca fascicularis, Mafa) have been used as important
experimental animal models for carrying out biomedical researches. The results of …

Complete sequencing of a cynomolgus macaque major histocompatibility complex haplotype

JA Karl, TM Prall, HE Bussan, JM Varghese… - Genome …, 2023 - genome.cshlp.org
Macaques provide the most widely used nonhuman primate models for studying the
immunology and pathogenesis of human diseases. Although the macaque major …

Genetic diversity and structural complexity of the killer-cell immunoglobulin-like receptor gene complex: A comprehensive analysis using human pangenome …

TK Hung, WC Liu, SK Lai, HW Chuang, YC Lee, HY Lin… - bioRxiv, 2023 - biorxiv.org
The killer-cell immunoglobulin-like receptor (KIR) gene complex, a highly polymorphic
region of the human genome that encodes proteins involved in immune responses, poses …

Restricted MHC class IA locus diversity in olive and hybrid olive/yellow baboons from the Southwest National Primate Research Center

RA Morgan, JA Karl, HE Bussan, KE Heimbruch… - Immunogenetics, 2018 - Springer
Baboons are valuable models for complex human diseases due to their genetic and
physiologic similarities to humans. Deep sequencing methods to characterize full-length …

Complete Genomic Assembly of Mauritian Cynomolgus Macaque Killer Ig-like Receptor and Natural Killer Group 2 Haplotypes

TM Prall, JA Karl, JM Varghese, DA Baker… - The Journal of …, 2024 - journals.aai.org
Mauritian-origin cynomolgus macaques (MCMs) serve as a powerful nonhuman primate
model in biomedical research due to their unique genetic homogeneity, which simplifies …