Like a number of neuropeptides, galanin can alter neural activity in brain areas that are
important for both stress-related behaviors and responses to drugs of abuse. Accordingly …

Galanin is a neuropeptide synthesized in many neuronal types including brainstem
norepinephrine-producing cells of the locus coeruleus and the serotonin-producing neurons …

Galanin is a 29 or 30 amino acid peptide with a close anatomical and neurophysiological
relationship with neural systems mediating stress. In rodent behavioral studies, the …

There is high comorbidity between stress-related psychiatric disorders and addiction,
suggesting they may share one or more common neurobiological mechanisms. Because of …

There has been increasing interest in the ability of neuropeptides involved in feeding to
modulate circuits important for responses to drugs of abuse. A number of peptides with …

Rationale Galanin and its receptors exert inhibitory neuromodulatory control over brain
monoamines. Rat studies revealed that galanin expression is upregulated by exposure to …

Galanin is a 29 amino-acid (30 in humans) neuropeptide with a close functional relationship
with neurotransmitter systems implicated in the pathophysiology and treatment of …

Accumulating evidence indicates that disruption of galanin signaling is associated with
neuropsychiatric disease, but the precise functions of this neuropeptide remain largely …

There has been increasing interest in the ability of neuropeptides involved in feeding to
modulate circuits important for responses to drugs of abuse. A number of peptides with …

Galanin and its receptors are expressed in brain areas associated with opiate reinforcement
and withdrawal. An emerging body of data suggests that galanin can attenuate the …