The highly diverse Antarctic Peninsula soil microbiota as a source of novel resistance genes

AE Marcoleta, P Arros, MA Varas, J Costa… - Science of the Total …, 2022 - Elsevier
The rise of multiresistant bacterial pathogens is currently one of the most critical threats to
global health, encouraging a better understanding of the evolution and spread of …

Functional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibiotics

GG Perron, L Whyte, PJ Turnbaugh, J Goordial… - PloS one, 2015 - journals.plos.org
Using functional metagenomics to study the resistomes of bacterial communities isolated
from different layers of the Canadian high Arctic permafrost, we show that microbial …

A reservoir of 'historical'antibiotic resistance genes in remote pristine Antarctic soils

MW Van Goethem, R Pierneef, OKI Bezuidt… - Microbiome, 2018 - Springer
Background Soil bacteria naturally produce antibiotics as a competitive mechanism, with a
concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic …

Influence of soil characteristics and proximity to Antarctic research stations on abundance of antibiotic resistance genes in soils

F Wang, RD Stedtfeld, OS Kim, B Chai… - … science & technology, 2016 - ACS Publications
Soil is an important environmental reservoir of antibiotic resistance genes (ARGs), which are
increasingly recognized as environmental contaminants. Methods to assess the risks …

[HTML][HTML] Antibiotic resistance in the environment

DG Larsson, CF Flach - Nature Reviews Microbiology, 2022 - nature.com
Antibiotic resistance is a global health challenge, involving the transfer of bacteria and
genes between humans, animals and the environment. Although multiple barriers restrict the …

Microbial regulation of natural antibiotic resistance: Understanding the protist-bacteria interactions for evolution of soil resistome

BAT Nguyen, QL Chen, JZ He, HW Hu - Science of the total environment, 2020 - Elsevier
The emergence, evolution and spread of antibiotic resistance genes (ARGs) in the
environment represent a global threat to human health. Our knowledge of antibiotic …

Insight into heavy metal resistome of soil psychrotolerant bacteria originating from King George Island (Antarctica)

K Romaniuk, A Ciok, P Decewicz, W Uhrynowski… - Polar Biology, 2018 - Springer
The presence of heavy metals in Antarctica is an emerging issue, especially as (bio)
weathering of metal-containing minerals occurs and human influence is more and more …

Ecology and evolution of antibiotic resistance

F Baquero, C Alvarez‐Ortega… - Environmental …, 2009 - Wiley Online Library
The evolution of bacterial pathogens towards antibiotic resistance is not just a relevant
problem for human health, but a fascinating example of evolution that can be studied in real …

[HTML][HTML] Role and prevalence of antibiosis and the related resistance genes in the environment

S Nazaret, R Aminov - Frontiers in Microbiology, 2014 - frontiersin.org
It becomes increasingly clear that the basis of antibiotic resistance problem among bacterial
pathogens is not confined to the borders of clinical microbiology but has broader ecological …

Interplay Between Antimicrobial Resistance and Global Environmental Change

MM Zambrano - Annual Review of Genetics, 2023 - annualreviews.org
Antibiotic resistance genes predate the therapeutic uses of antibiotics. However, the current
antimicrobial resistance crisis stems from our extensive use of antibiotics and the generation …