The Effect of Different Exercise Modalities on Sertoli-germ Cells Metabolic Interactions in High-fat Diet-induced Obesity Rat Models: Implication on Glucose and …

AH Maleki, JT Azar, M Razi, A Tofighi - Reproductive Sciences, 2024 - Springer
The study aimed to uncover a unique aspect of obesity-related metabolic disorders in the
testicles induced by a high-fat diet (HFD) and explored the potential mitigating effects of …

Different continuous exercise training intensities induced effect on sertoli-germ cells metabolic interaction; implication on GLUT-1, GLUT-3 and MCT-4 transporting …

P Soudmand, A Tofighi, JT Azar, M Razi, FG Pakdel - Gene, 2021 - Elsevier
Despite other tissues, the effect of different exercise training protocols (ETPs) on the
expression levels of metabolic substrates transmembrane transporters in the testicular …

Exercise improves testicular morphology and oxidative stress parameters in rats with testicular damage induced by a high‐fat diet

MA Elmas, OB Ozakpinar, M Kolgazi, G Sener… - Andrologia, 2022 - Wiley Online Library
Obesity and male infertility are problems that affect population. Exercise is a
nonpharmacological way to reduce the negative health effects of obesity. The purpose of …

High‐energy diets may induce a pre‐diabetic state altering testicular glycolytic metabolic profile and male reproductive parameters

L Rato, MG Alves, TR Dias, G Lopes, JE Cavaco… - …, 2013 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that may arise from diet habits and is growing to
epidemic proportions. Young male diabetic patients present high infertility/subfertility …

[HTML][HTML] Exercise protects against obesity induced semen abnormalities via downregulating stem cell factor, upregulating Ghrelin and normalizing oxidative stress

F Alhashem, M Alkhateeb, H Sakr, M Alshahrani… - EXCLI …, 2014 - ncbi.nlm.nih.gov
Increased oxidative stress and hormonal imbalance have been hypothesized to underlie
infertility in obese animals. However, recent evidence suggests that Ghrelin and Stem Cell …

The effect of different types of exercise training on diet-induced obesity in rats, cross-talk between cell cycle proteins and apoptosis in testis

JT Azar, AH Maleki, S Moshari, M Razi - Gene, 2020 - Elsevier
Obesity is associated with germ cell apoptosis, spermatogenesis arrest, and testicular
endocrine suppression. The aim of the present study was to investigate the crosstalk …

Altered endocrine, cytokine signaling and oxidative stress: a plausible reason for differential changes in testicular cells in diet-induced and genetically-inherited …

SS Deshpande, H Nemani, S Pothani… - Reproductive Biology, 2019 - Elsevier
Obesity is emerging as a potential risk factor for male infertility. It is a multifactorial disorder
with primarily genetic and/or environmental factors. Our earlier studies have shown …

Effect of aerobic exercise, low‐fat and high‐fat diet on the testis tissue and sperm parameters in obese and nonobese mice model

A Nematollahi, F Kazeminasab, M Tavalaee… - Andrologia, 2019 - Wiley Online Library
Semen quality and male fertility depend on numerous factors such as age, environment,
lifestyle, physical activity, genetic background and occupation. We aimed to access the effect …

A high fat diet during adolescence in male rats negatively programs reproductive and metabolic function which is partially ameliorated by exercise

CA Ibanez, RP Erthal, FM Ogo, MNC Peres… - Frontiers in …, 2017 - frontiersin.org
An interaction between obesity, impaired glucose metabolism and sperm function in adults
has been observed but it is not known whether exposure to a diet high in fat during the peri …

Caloric restriction alters the hormonal profile and testicular metabolome, resulting in alterations of sperm head morphology

AD Martins, I Jarak, T Morais… - American Journal …, 2020 - journals.physiology.org
Energy homeostasis is crucial for all physiological processes. Thus, when there is low
energy intake, negative health effects may arise, including in reproductive function. We …