The mechanism of vesicle solubilization by the detergent sodium dodecyl sulfate

J Juan-Colás, L Dresser, K Morris, H Lagadou… - Langmuir, 2020 - ACS Publications
Membrane solubilization by sodium dodecyl sulfate (SDS) is indispensable for many
established biotechnological applications, including viral inactivation and protein extraction …

Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents

PA Dalgarno, J Juan-Colás, GJ Hedley, L Piñeiro… - Scientific reports, 2019 - nature.com
The solubilization of membranes by detergents is critical for many technological applications
and has become widely used in biochemistry research to induce cell rupture, extract cell …

Pathways of membrane solubilization: A structural study of model lipid vesicles exposed to classical detergents

VA Bjørnestad, R Lund - Langmuir, 2023 - ACS Publications
Understanding the pathways of solubilization of lipid membranes is of high importance for
their use in biotechnology and industrial applications. Although lipid vesicle solubilization by …

[HTML][HTML] Solubilization kinetics determines the pulsatory dynamics of lipid vesicles exposed to surfactant

M Chabanon, P Rangamani - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
We establish a biophysical model for the dynamics of lipid vesicles exposed to surfactants.
The solubilization of the lipid membrane due to the insertion of surfactant molecules induces …

[HTML][HTML] Thermodynamics of lipid membrane solubilization by sodium dodecyl sulfate

S Keller, H Heerklotz, N Jahnke, A Blume - Biophysical journal, 2006 - cell.com
We provide a comprehensive thermodynamic description of lipid membrane dissolution by a
charged detergent. To this end, we have studied the interactions between the anionic …

Size-dependent, stochastic nature of lipid exchange between nano-vesicles and model membranes

SR Tabaei, JJJ Gillissen, S Vafaei, JT Groves, NJ Cho - Nanoscale, 2016 - pubs.rsc.org
The interaction of nanoscale lipid vesicles with cell membranes is of fundamental
importance for the design and development of vesicular drug delivery systems. Here, we …

The mechanism of detergent solubilization of liposomes and protein-containing membranes

U Kragh-Hansen, M le Maire, JV Møller - Biophysical journal, 1998 - cell.com
The present study explores intermediate stages in detergent solubilization of liposomes and
Ca 2+-ATPase membranes by sodium dodecyl sulfate (SDS) and medium-sized (∼ C 12) …

Inserting small molecules across membrane mixtures: Insight from the potential of mean force

A Centi, A Dutta, SH Parekh, T Bereau - Biophysical Journal, 2020 - cell.com
Small solutes have been shown to alter the lateral organization of cell membranes and
reconstituted phospholipid bilayers; however, the mechanisms by which these changes …

Physicochemical profiling of surfactant-induced membrane dynamics in a cell-sized liposome

T Hamada, H Hagihara, M Morita… - The Journal of …, 2012 - ACS Publications
We used a cell-sized model system, giant liposomes, to investigate the interaction between
lipid membranes and surfactants, and the membrane transformation during the solubilization …

Deciphering how pore formation causes strain-induced membrane lysis of lipid vesicles

JA Jackman, HZ Goh, VP Zhdanov… - Journal of the …, 2016 - ACS Publications
Pore formation by membrane-active antimicrobial peptides is a classic strategy of pathogen
inactivation through disruption of membrane biochemical gradients. It remains unknown why …