Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation
E Laborel-Préneron, P Bianchi, F Boralevi, P Lehours… - PLoS …, 2015 - journals.plos.org
Interactions between the immune system and skin bacteria are of major importance in the
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …
Microbiome and pediatric atopic dermatitis
CE Powers, DB McShane, PH Gilligan… - The Journal of …, 2015 - Wiley Online Library
Atopic dermatitis is a chronic inflammatory skin condition with drastic impacts on pediatric
health. The pathogenesis of this common disease is not well understood, and the complex …
health. The pathogenesis of this common disease is not well understood, and the complex …
Nasal and skin microbiomes are associated with disease severity in paediatric atopic dermatitis
Background Alterations of the skin microbiome have been associated with atopic dermatitis
(AD) and its severity. The nasal microbiome in relation to AD severity is less well studied …
(AD) and its severity. The nasal microbiome in relation to AD severity is less well studied …
Role of the microbiota in skin immunity and atopic dermatitis
Y Yamazaki, Y Nakamura, G Núñez - Allergology International, 2017 - jstage.jst.go.jp
abstract Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 15e20% of
children and 2e5% of adults in industrialized countries. The pathogen Staphylococcus …
children and 2e5% of adults in industrialized countries. The pathogen Staphylococcus …
The skin microbiome of patients with atopic dermatitis normalizes gradually during treatment
Background Atopic dermatitis (AD) is characterized by an altered skin microbiome
dominantly colonized by S. aureus. Standard treatment includes emollients, anti …
dominantly colonized by S. aureus. Standard treatment includes emollients, anti …
Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis
AL Byrd, C Deming, SKB Cassidy… - Science translational …, 2017 - science.org
The heterogeneous course, severity, and treatment responses among patients with atopic
dermatitis (AD; eczema) highlight the complexity of this multifactorial disease. Prior studies …
dermatitis (AD; eczema) highlight the complexity of this multifactorial disease. Prior studies …
Regulation of T cell immunity in atopic dermatitis by microbes: the yin and yang of cutaneous inflammation
T Biedermann, Y Skabytska, S Kaesler… - Frontiers in …, 2015 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease predominantly mediated by T
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …
Cutaneous dysbiosis may amplify barrier dysfunction in patients with atopic dermatitis
M Hammond, A Gamal, PK Mukherjee… - Frontiers in …, 2022 - frontiersin.org
Atopic dermatitis (AD) is associated with cutaneous dysbiosis, barrier defects, and immune
dysregulation, but the interplay between these factors needs further study. Early-onset …
dysregulation, but the interplay between these factors needs further study. Early-onset …
Skin microbiome dysbiosis and the role of Staphylococcus aureus in atopic dermatitis in adults and children: A narrative review
AL Demessant‐Flavigny, S Connétable… - Journal of the …, 2023 - Wiley Online Library
A dysfunctional epidermal barrier, which may be associated with mutations in the filaggrin
gene in genetically predisposed individuals or harmful effects of environmental agents and …
gene in genetically predisposed individuals or harmful effects of environmental agents and …
The role of the skin microbiome in atopic dermatitis
T Nakatsuji, RL Gallo - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease associated with significant
medical burden, affecting 15% to 20% of children and 1% to 3% of adults worldwide. 1 The …
medical burden, affecting 15% to 20% of children and 1% to 3% of adults worldwide. 1 The …