Asthma is a chronic heterogeneous respiratory condition that is mainly associated with
sensitivity to airborne agents such as pollen, dust mite products and fungi. Key pathological …

For decades, fungi have been recognized as associated with asthma and other reactive
airway diseases. In contrast to type I-mediated allergies caused by pollen, fungi cause a …

Introduction 3. Airway Remodeling in Allergic Asthma 4. Airway Wall Remodeling in Patients
with ABPA 5. Interaction of Airway Epithelium with Aspergillus 6. Aspergillus Proteolytic …

Background Asthma is a chronic inflammatory condition of the airways and patients
sensitized to airborne fungi such as Aspergillus fumigatus have more severe asthma …

Although fungi are pervasive in many environments, few cause disease in humans. Of these,
Aspergillus fumigatus is particularly well suited to be a pathogen of the human lung. Its …

Aspergillus moulds exist ubiquitously as spores that are inhaled in large numbers daily.
Whilst most are removed by anatomical barriers, disease may occur in certain …

Background In susceptible individuals, exposure to Aspergillus fumigatus can lead to the
development of atopic lung diseases such as allergic bronchopulmonary aspergillosis …

Abstract Background Aspergillus fumigatus (Af) sometimes colonizes and persists within the
respiratory tree in some patients with asthma. To date, the precise reasons why the …

Allergic asthma is a debilitating disease of the airways characterized by airway
hyperresponsiveness, eosinophilic inflammation, goblet cell metaplasia with associated …

Clinical allergic airway disease is associated with persistent airway hyperreactivity and
remodeling, but little is known about the mechanisms leading to these alterations. This …