Control of RNA stability in immunity
S Akira, K Maeda - Annual review of immunology, 2021 - annualreviews.org
Posttranscriptional control of mRNA regulates various biological processes, including
inflammatory and immune responses. RNA-binding proteins (RBPs) bind cis-regulatory …
inflammatory and immune responses. RNA-binding proteins (RBPs) bind cis-regulatory …
Posttranscriptional regulation of cytokine mRNA controls the initiation and resolution of inflammation
O Takeuchi - Chronic Inflammation: Mechanisms and Regulation, 2016 - Springer
Excess or sustained production of cytokines in innate immune cells leads to the
development of chronic inflammatory diseases, such as autoimmune diseases. In …
development of chronic inflammatory diseases, such as autoimmune diseases. In …
Post-transcriptional regulation of immune responses by RNA binding proteins
T Mino, O Takeuchi - Proceedings of the Japan Academy, Series B, 2018 - jstage.jst.go.jp
Cytokines are critical mediators of inflammation and host immune defense. Cytokine
production is regulated at both transcriptional and post-transcriptional levels. Post …
production is regulated at both transcriptional and post-transcriptional levels. Post …
Post‐transcriptional regulatory networks in immunity
P Ivanov, P Anderson - Immunological reviews, 2013 - Wiley Online Library
Post‐transcriptional mechanisms that modulate global and/or transcript‐specific m RNA
stability and translation contribute to the rapid and flexible control of gene expression in …
stability and translation contribute to the rapid and flexible control of gene expression in …
[HTML][HTML] Uncovering the role of RNA-binding proteins in gene expression in the immune system
MD Díaz-Muñoz, M Turner - Frontiers in immunology, 2018 - frontiersin.org
Fighting external pathogens requires an ever-changing immune system that relies on tight
regulation of gene expression. Transcriptional control is the first step to build efficient …
regulation of gene expression. Transcriptional control is the first step to build efficient …
[HTML][HTML] RBP–RNA interactions in the control of autoimmunity and autoinflammation
J Liu, X Cao - Cell research, 2023 - nature.com
Autoimmunity and autoinflammation arise from aberrant immunological and inflammatory
responses toward self-components, contributing to various autoimmune diseases and …
responses toward self-components, contributing to various autoimmune diseases and …
RNA-binding proteins control gene expression and cell fate in the immune system
M Turner, MD Díaz-Muñoz - Nature immunology, 2018 - nature.com
RNA-binding proteins (RBPs) are essential for the development and function of the immune
system. They interact dynamically with RNA to control its biogenesis and turnover by …
system. They interact dynamically with RNA to control its biogenesis and turnover by …
Arid5a, an RNA-binding protein in immune regulation: RNA stability, inflammation, and autoimmunity
AT-rich interactive domain 5A (ARID5A/Arid5a) is a known cofactor of transcription factors
(TFs) that contributes to cell growth and differentiation. It has recently been recognized for its …
(TFs) that contributes to cell growth and differentiation. It has recently been recognized for its …
Roles of RNA-binding proteins in immune diseases and cancer
S Hashimoto, T Kishimoto - Seminars in cancer biology, 2022 - Elsevier
Genetic information that is transcribed from DNA to mRNA, and then translated from mRNA
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …
Translating the untranslated region
J Schwerk, R Savan - The Journal of Immunology, 2015 - journals.aai.org
Gene expression programs undergo constant regulation to quickly adjust to environmental
stimuli that alter the physiological status of the cell, like cellular stress or infection. Gene …
stimuli that alter the physiological status of the cell, like cellular stress or infection. Gene …