Excessive alcohol intake, eg, binge drinking, is a serious and mounting public health
problem in the United States and throughout the world. Hence the need for novel insights …

Background There is no countable biomarker for opioid dependence treatment responses
thus far. In this study, we recruited Taiwanese methadone maintenance treatment patients to …

Background In an initial study, we reported that topiramate reduced heavy drinking among
individuals who sought to reduce their drinking and that the effect was moderated by a …

The firing of mesolimbic dopamine neurons is important for drug-induced reinforcement,
although underlying genetic factors remain poorly understood. In a recent genome-wide …

Annotated bibliography of genetic addiction risk severity (GARS) publications, pro-dopamine
regulation in nutraceuticals (KB220 nutraceutical variants), and policy documents. Further …

Background & aim: The dopaminergic pathways have been implicated in the etiology of drug
addictions. The aim of this study was to determine if variants in dopaminergic genes are …

175 1. ABSTRACT Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid
dependence Kenneth Blum1-8,10,18 Page 1 175 1. ABSTRACT The interaction of …

Adaptations in the anterior cingulate cortex (ACC) have been implicated in alcohol and drug
addiction. To identify genes that may contribute to excessive drinking, here we performed …

This article describes a unique therapeutic precision intervention, a formulation of
enkephalinase inhibitors, enkephalin, and dopamine-releasing neuronutrients, to induce …

It is universally agreed that dopamine is a major neurotransmitter in terms of reward
dependence, however, there remains controversy regarding how to modulate its role …