[HTML][HTML] Combinatory effect and modes of action of chrysin and bone marrow-derived mesenchymal stem cells on streptozotocin/nicotinamide-induced diabetic rats

HM Sayed, AS Awaad, FEZS Abdel Rahman… - Pharmaceuticals, 2022 - mdpi.com
The purpose of this study was to see how chrysin and/or bone marrow-derived
mesenchymal stem cells (BM-MSCs) affected streptozotocin (STZ)/nicotinamide (NA) …

[HTML][HTML] Efficiency of bone marrow-derived mesenchymal stem cells and hesperetin in the treatment of streptozotocin-induced type 1 diabetes in Wistar rats

OM Ahmed, AS Saleh, EA Ahmed, MM Ghoneim… - Pharmaceuticals, 2023 - mdpi.com
Type 1 diabetes mellitus (T1DM) was established to be ameliorated by islet transplantation,
but the shortage of the transplanted human islet tissue and the use of immunosuppressive …

Evaluation of in vivo and ex vivo pre-treated bone marrow-derived mesenchymal stem cells with resveratrol in streptozotocin-induced type 1 diabetic rats

SG Khalil, NN Younis, MA Shaheen… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To compare the therapeutic potential of rat bone marrow-derived mesenchymal
stem cells (BM-MSCs) preconditioned ex-vivo with resveratrol (MCR) and BM-MSCs isolated …

Mesenchymal stem cells ameliorate hyperglycemia in type I diabetic developing male rats

HN Yousef, SM Sakr, SA Sabry - Stem cells international, 2022 - Wiley Online Library
One of the most promising treatments for diabetes mellitus (DM) is stem cell therapy. This
study is aimed at elucidating the antidiabetic effect of mesenchymal stem cells (MSCs) on …

[HTML][HTML] Co-treatment with grape seed extract and mesenchymal stem cells in vivo regenerated beta cells of islets of Langerhans in pancreas of type I-induced diabetic …

A Farid, H Haridyy, S Ashraf, S Ahmed… - Stem Cell Research & …, 2022 - Springer
Background Nowadays, diabetes mellitus is known as a silent killer because individual is
not aware that he has the disease till the development of its complications. Many …

Chrysin attenuates high glucose-induced BMSC dysfunction via the activation of the PI3K/AKT/Nrf2 signaling pathway

Y Li, X Wang - Drug Design, Development and Therapy, 2022 - Taylor & Francis
Purpose High glucose environment in diabetes mellitus induces the dysfunction of bone
marrow-derived mesenchymal stromal cells (BMSCs) and impairs bone regeneration …

Effect of combined therapy of human Wharton's jelly-derived mesenchymal stem cells from umbilical cord with sitagliptin in type 2 diabetic rats

J Hu, F Wang, R Sun, Z Wang, X Yu, L Wang, H Gao… - Endocrine, 2014 - Springer
Type 2 diabetes mellitus is the most common endocrine disease all over the world, while
existing therapies can only ameliorate hyperglycemia or temporarily improve the response …

Chrysin treatment improves diabetes and its complications in liver, brain, and pancreas in streptozotocin-induced diabetic rats

S Samarghandian, M Azimi-Nezhad… - Canadian journal of …, 2016 - cdnsciencepub.com
Chrysin (CH) is a natural flavonoid with pharmacological influences. The purpose of the
current study was the assessment of possible protective effects of CH against oxidative …

[HTML][HTML] Chrysin induces antidiabetic, antidyslipidemic and anti-inflammatory effects in athymic nude diabetic mice

JJ Ramírez-Espinosa, J Saldaña-Ríos… - Molecules, 2017 - mdpi.com
Extensive knowledge of diabetes and its complications is helpful to find new drugs for proper
treatment to stop degenerative changes derived from this disease. In this context, chrysin (5 …

Effect of mesenchymal stem cell therapy on recovery of streptozotocin-induced diabetes mellitus in adult male albino rats: a histological and immunohistochemical …

NM Afifi - Egyptian journal of histology, 2012 - journals.lww.com
Aim of the work The present study was carried out to investigate the therapeutic effect of
mesenchymal stem cells (MSCs) in the recovery of streptozotocin (STZ)-induced diabetes …