Genetic predisposition to prostate cancer: update and future perspectives
F Demichelis, JL Stanford - Urologic Oncology: Seminars and Original …, 2015 - Elsevier
Objective Prostate cancer is the second most frequent cancer in men worldwide and kills
over 250,000 men worldwide every year. Prostate cancer is a heterogeneous disease at the …
over 250,000 men worldwide every year. Prostate cancer is a heterogeneous disease at the …
Genetic variants associated with predisposition to prostate cancer and potential clinical implications
CL Goh, FR Schumacher, D Easton… - Journal of internal …, 2012 - Wiley Online Library
Goh CL, Schumacher FR, Easton D, Muir K, Henderson B, Kote‐Jarai Z, Eeles RA (The
Institute of Cancer Research, Sutton, Surrey, UK; Keck School of Medicine, University of …
Institute of Cancer Research, Sutton, Surrey, UK; Keck School of Medicine, University of …
Rare germline genetic variants and risk of aggressive prostate cancer
T Nguyen‐Dumont, RJ MacInnis… - … journal of cancer, 2020 - Wiley Online Library
Few genetic risk factors have been demonstrated to be specifically associated with
aggressive prostate cancer (PrCa). Here, we report a case‐case study of PrCa comparing …
aggressive prostate cancer (PrCa). Here, we report a case‐case study of PrCa comparing …
The genetic epidemiology of prostate cancer and its clinical implications
R Eeles, C Goh, E Castro, E Bancroft, M Guy… - Nature reviews …, 2014 - nature.com
Worldwide, familial and epidemiological studies have generated considerable evidence of
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …
Genetic predisposition to prostate cancer: an update
H Ni Raghallaigh, R Eeles - Familial Cancer, 2022 - Springer
Improvements in DNA sequencing technology and discoveries made by large scale genome-
wide association studies have led to enormous insight into the role of genetic variation in …
wide association studies have led to enormous insight into the role of genetic variation in …
Germline genetic variants associated with prostate cancer and potential relevance to clinical practice
CL Goh, RA Eeles - Prostate cancer prevention, 2014 - Springer
The inherited link of prostate cancer predisposition has been supported using data from
early epidemiological studies, as well as from familial and twin studies. Early linkage …
early epidemiological studies, as well as from familial and twin studies. Early linkage …
Genetics of prostate cancer risk
MM Pomerantz, ML Freedman - Mount Sinai Journal of …, 2010 - Wiley Online Library
Abstract table 2 check and delte For decades, physicians and researchers have recognized
that family history is a significant risk factor for prostate cancer. The identification of the …
that family history is a significant risk factor for prostate cancer. The identification of the …
The clinical genetics of prostate cancer
S Kommu, S Edwards, R Eeles - Hereditary Cancer in Clinical Practice, 2004 - Springer
Prostate cancer is the most common cancer in men and the second highest cause of cancer-
related mortality in the UK A genetic component in predisposition to prostate cancer has …
related mortality in the UK A genetic component in predisposition to prostate cancer has …
Prostate cancer risk variants are not associated with disease progression
R Szulkin, E Holmberg, P Stattin, J Xu, S Zheng… - The …, 2012 - Wiley Online Library
BACKGROUND Currently used prognostic markers are limited in their ability to accurately
predict disease progression among patients with localized prostate cancer. We examined 23 …
predict disease progression among patients with localized prostate cancer. We examined 23 …
[PDF][PDF] Prostate cancer predisposition
The three most important recognized risks for prostate cancer (PCa) are increasing age,
ancestry, and family history of the disease. The clustering of PCa within families can be …
ancestry, and family history of the disease. The clustering of PCa within families can be …