Alzheimer disease (AD) is the leading cause of dementia among elderly. Currently, no
effective treatment is available for AD. Analysis of transgenic mouse models of AD has …

This review describes several transgenic mouse models of Alzheimer's disease (AD), a
devastating neurodegenerative disorder that causes progressive cognitive decline and is …

Alzheimer's disease (AD), an irreversible neurodegenerative disease that progressively
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …

Abstract Alzheimer's disease (AD), for which there is no cure, is the most common form of
dementia in the elderly. Despite tremendous efforts by the scientific community, the AD drug …

During the past 2 decades, the elucidation of susceptibility and causative genes for
Alzheimer disease as well as proteins involved in the pathogenic process has greatly …

Alzheimer's disease (AD) is one of the looming health crises of the near future. Increasing
lifespans and better medical treatment for other conditions mean that the prevalence of this …

Alzheimer's disease is the most common cause of senile dementia in the United States and
Europe. At present, there is no effective treatment. Given the disease's prevalence and poor …

Alzheimer's disease (AD) is the most common form of dementia. At the diagnostic stage, the
AD brain is characterized by the accumulation of extracellular amyloid plaques, intracellular …

Alzheimer's disease (AD) is the most common neurodegenerative disease and cause of
dementia. Significant strides toward understanding and developing therapies for AD have …

Significant insights into the function of genes associated with Alzheimer disease and related
dementias have occurred through studying genetically modified animals. Although none of …