[HTML][HTML] In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges
Within less than a decade since its inception, CRISPR-Cas9-based genome editing has
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
Delivery of CRISPR/Cas9 by novel strategies for gene therapy
Precise editing of the genome of a living body is a goal pursued by scientists in many fields.
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas …
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas …
CRISPR/Cas9 delivery system engineering for genome editing in therapeutic applications
H Cheng, F Zhang, Y Ding - Pharmaceutics, 2021 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
Progress of delivery methods for CRISPR-Cas9
Introduction Gene therapy is becoming increasingly common in clinical practice, giving hope
for the correction of a wide range of human diseases and defects. The CRISPR/Cas9 …
for the correction of a wide range of human diseases and defects. The CRISPR/Cas9 …
Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
Delivery approaches for CRISPR/Cas9 therapeutics in vivo: advances and challenges
Introduction: Therapeutic gene editing is becoming a viable biomedical tool with the
emergence of the CRISPR/Cas9 system. CRISPR-based technologies have promise as a …
emergence of the CRISPR/Cas9 system. CRISPR-based technologies have promise as a …
CRISPR-Cas9 for in vivo gene therapy: Promise and hurdles
WJ Dai, LY Zhu, ZY Yan, Y Xu, QL Wang… - Molecular Therapy-Nucleic …, 2016 - cell.com
Owing to its easy-to-use and multiplexing nature, the genome editing tool CRISPR-Cas9
(clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9) …
(clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9) …
Rational designs of in vivo CRISPR-Cas delivery systems
The CRISPR-Cas system initiated a revolution in genome editing when it was, for the first
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …
Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing
The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 genome
editing system has been a major technological breakthrough that has brought revolutionary …
editing system has been a major technological breakthrough that has brought revolutionary …
CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential
EO Blenke, MJW Evers, E Mastrobattista… - Journal of Controlled …, 2016 - Elsevier
The CRISPR-Cas9 gene editing system has taken the biomedical science field by storm,
initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also …
initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also …