[HTML][HTML] Surgery after conversion therapy with PD-1 inhibitors plus tyrosine kinase inhibitors are effective and safe for advanced hepatocellular carcinoma: a pilot study …

W Zhang, B Hu, J Han, Z Wang, G Ma, H Ye… - Frontiers in …, 2021 - frontiersin.org
Background and Aims Immunotherapy with PD-1 inhibitors combined with tyrosine kinase
inhibitors (TKIs) has been proven to be effective against advanced hepatocellular carcinoma …

[HTML][HTML] Hepatectomy after conversion therapy using tyrosine kinase inhibitors plus anti-PD-1 antibody therapy for patients with unresectable hepatocellular carcinoma

XD Zhu, C Huang, YH Shen, B Xu, NL Ge, Y Ji… - Annals of surgical …, 2023 - Springer
Background Combined treatment with tyrosine kinase inhibitors (TKI) plus anti-PD-1
antibodies showed high anti-tumor efficacy and made conversion resection possible for …

[HTML][HTML] Surgical conversion for initially unresectable locally advanced hepatocellular carcinoma using a triple combination of angiogenesis inhibitors, anti-PD-1 …

J Zhang, X Zhang, H Mu, G Yu, W Xing, L Wang… - Frontiers in …, 2021 - frontiersin.org
Background Recent research has shown that selected patients with initially unresectable
hepatocellular carcinoma (HCC) are able to achieve conversion to resectable disease …

[HTML][HTML] Downstaging and resection of initially unresectable hepatocellular carcinoma with tyrosine kinase inhibitor and anti-PD-1 antibody combinations

XD Zhu, C Huang, YH Shen, Y Ji, NL Ge, XD Qu… - Liver cancer, 2021 - karger.com
Background: Combined therapy with tyrosine kinase inhibitors (TKIs) and anti-PD-1
antibodies has shown high tumor response rates for patients with unresectable …

Efficacy and safety of PD‐1 inhibitor combined with antiangiogenic therapy for unresectable hepatocellular carcinoma: A multicenter retrospective study

J Yao, X Zhu, Z Wu, Q Wei, Y Cai, Y Zheng… - Cancer …, 2022 - Wiley Online Library
Background Immunotherapy‐antiangiogenesis combination therapy has achieved excellent
survival outcomes in hepatocellular carcinoma (HCC) in clinical trials. However, the …

Conversion surgery after preoperative therapy for advanced hepatocellular carcinoma in the era of molecular targeted therapy and immune checkpoint inhibitors

J Arita, A Ichida, R Nagata, Y Mihara… - Journal of Hepato …, 2022 - Wiley Online Library
Background Optimal strategies for advanced hepatocellular carcinoma (HCC) tumors, such
as those with vascular tumor thrombus and those with extrahepatic metastases are unclear …

[HTML][HTML] Downstaging and resection of hepatocellular carcinoma in patients with extrahepatic metastases after stereotactic therapy

X Yang, H Xu, B Zuo, X Yang, J Bian… - … surgery and nutrition, 2021 - ncbi.nlm.nih.gov
Background A combination of tyrosine kinase inhibitors (TKIs) and anti-PD-1 antibodies with
local regional therapy has elicited yield substantial clinical benefits in patients who have …

Conversion therapy with an immune checkpoint inhibitor and an antiangiogenic drug for advanced hepatocellular carcinoma: A review

H Tang, Y Cao, Y Jian, X Li, J Li, W Zhang, T Wan… - BioScience …, 2022 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) has been the fifth most common malignancy worldwide
and is the second most common cause of tumor-related mortality globally. In China, a high …

[HTML][HTML] Safety of PD-1/PD-L1 inhibitors combined with palliative radiotherapy and anti-angiogenic therapy in advanced hepatocellular carcinoma

L Zhong, D Wu, W Peng, H Sheng, Y Xiao… - Frontiers in …, 2021 - frontiersin.org
Background Previous studies have explored cancer immunotherapy with radiotherapy or
anti-angiogenic therapy, but no trials have reported a triple therapy approach. This study …

Outcomes of salvage surgery for initially unresectable hepatocellular carcinoma converted by transcatheter arterial chemoembolization combined with lenvatinib plus …

JY Wu, ZB Zhang, JY Zhou, JP Ke, YN Bai, YF Chen… - Liver cancer, 2023 - karger.com
Introduction: The actual rate of conversion surgery and its prognostic advantages remain
unclear. This study aimed to assess the outcomes of salvage surgery after conversion …