Gut microbial regulation of organismal health through Tachykinin in Drosophila

DE Marcu - 2024 - theses.gla.ac.uk
The complex relationship between the gut microbiota and host physiology is a multifaceted
area of investigation with profound implications for systemic health and ageing. Despite …

THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER

H NAJJAR - 2021 - qspace.qu.edu.qa
The intestine of all living organisms fosters an ecosystem of commensal microbiota that
plays key roles in the maintenance of host health and pathology. Captivatingly, the influence …

Microbial control of intestinal homeostasis via enteroendocrine cell innate immune signaling

PI Watnick, BE Jugder - Trends in microbiology, 2020 - cell.com
A community of commensal microbes, known as the intestinal microbiota, resides within the
gastrointestinal tract of animals and plays a role in maintenance of host metabolic …

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

N Buchon, NA Broderick, S Chakrabarti… - Genes & …, 2009 - genesdev.cshlp.org
Gut homeostasis is controlled by both immune and developmental mechanisms, and its
disruption can lead to inflammatory disorders or cancerous lesions of the intestine. While the …

How Gut Microbes Nurture Intestinal Stem Cells: A Drosophila Perspective

C Neophytou, C Pitsouli - Metabolites, 2022 - mdpi.com
Host-microbiota interactions are key modulators of host physiology and behavior.
Accumulating evidence suggests that the complex interplay between microbiota, diet and …

Drosophila as a model system for deciphering the 'host physiology–nutrition–microbiome'axis

JH Lee, KA Lee, WJ Lee - Current Opinion in Insect Science, 2020 - Elsevier
For metazoans, nutritional stressors, such as undernutrition during growth and development,
results in serious outcomes, including growth impairments and organ wasting. When …

Is the regulation of insulin signaling multi-organismal?

AE Douglas - Science signaling, 2011 - science.org
The sustained health of an individual animal depends on the composition and activities of its
resident microbiota. A major challenge is to identify the processes by which the microbiota …

[HTML][HTML] Transient adult microbiota, gut homeostasis and longevity: novel insights from the Drosophila model

B Erkosar, F Leulier - FEBS letters, 2014 - Elsevier
In the last decade, Drosophila has emerged as a useful model to study host–microbiota
interactions, creating an active research field with prolific publications. In the last 2 years …

Protein-responsive gut hormone Tachykinin directs food choice and impacts lifespan in Drosophila

K Rewitz, N Ahrentlov, O Kubrak, A Malita, T Koyama… - 2024 - researchsquare.com
Animals select food based on hungers that reflect dynamic and specific macronutrient
needs. Feeding behavior is governed by endocrine signals, but the hormonal mechanisms …

Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan

T Onuma, T Yamauchi, H Kosakamoto… - PLoS …, 2023 - journals.plos.org
Commensal microbes in animals have a profound impact on tissue homeostasis, stress
resistance, and ageing. We previously showed in Drosophila melanogaster that Acetobacter …