A basic overview of multiple sclerosis immunopathology

N Grigoriadis, V Van Pesch - European journal of neurology, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a multi‐component disease characterized by inflammation,
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …

Inflammation and axon degeneration

VH Perry, D Phil - Multiple Sclerosis as a Neuronal Disease, 2005 - books.google.com
Multiple sclerosis (MS) is the archetypal inflammatory demyelinating disease of the central
nervous system (CNS). It is widely believed to be an autoimmune disease in which the …

Multiple sclerosis: a battle between destruction and repair

JL McQualter, CCA Bernard - Journal of neurochemistry, 2007 - Wiley Online Library
Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS in which an
unrelenting attack from the innate and adaptive arms of the immune system results in …

The pathogenesis of multiple sclerosis: relating human pathology to experimental studies

SK Ludwin - Journal of Neuropathology & Experimental …, 2006 - academic.oup.com
Multiple sclerosis (MS) is a complex disease of unknown etiology. A careful study of the
pathology of its component elements in relation to relevant experimental models has helped …

Approaches to neuroprotective strategies in multiple sclerosis

A Tselis, OA Khan, RP Lisak - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: Multiple sclerosis (MS) is a neurologic disease that is the most
common nontraumatic cause of serious disability in young adults. Areas covered in this …

Cortical and meningeal pathology in progressive multiple sclerosis: a new therapeutic target?

BA Silva, CC Ferrari - Reviews in the Neurosciences, 2019 - degruyter.com
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease that involves an
intricate interaction between the central nervous system and the immune system …

What drives disease in multiple sclerosis: inflammation or neurodegeneration?

H Lassmann - Clinical and Experimental Neuroimmunology, 2010 - Wiley Online Library
Multiple sclerosis (MS) is defined as a chronic inflammatory disease of the central nervous
system, which leads to focal inflammatory demyelinated lesions with secondary …

[HTML][HTML] Inflammation, demyelination, and degeneration—recent insights from MS pathology

C Stadelmann, C Wegner, W Brück - Biochimica et Biophysica Acta (BBA) …, 2011 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
which responds to anti-inflammatory treatments in the early disease phase. However, the …

Review of the biology of multiple sclerosis

B Nourbakhsh - JAMA Neurology, 2013 - jamanetwork.com
Multiple sclerosis (MS) is the most common cause of neurological disability in young adults.
The past 2 decades have witnessed an ever-increasing number of promising treatments for …

Pathological mehanisms and disease progression of multiple sclerosis: therapeutic implications

C Bjartmar, RJ Fox - Drugs of Today, 2002 - access.portico.org
Introduction Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of
the central nervous system and a major cause of nontraumatic neurological disability among …