Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal

MJ Lee, SY Lee, S Cho, ES Kang… - The journal of headache …, 2018 - Springer
Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in
chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in …

Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine

E Cernuda-Morollón, D Larrosa, C Ramón, J Vega… - Neurology, 2013 - AAN Enterprises
Objective: To determine calcitonin gene-related peptide (CGRP) levels outside migraine
attacks in peripheral blood as a potential biomarker for chronic migraine (CM). Methods …

Calcitonin gene-related peptide in peripheral blood as a biomarker for migraine

C Ramón, E Cernuda-Morollón… - Current Opinion in …, 2017 - journals.lww.com
Although CGRP data must be confirmed and expanded in future studies and specificity of
CGRP levels should be studied in entities able to resemble migraine, it seems that …

Serum Alpha and Beta‐CGRP Levels in Chronic Migraine Patients Before and After Monoclonal Antibodies Against CGRP or its Receptor

G Gárate, V González‐Quintanilla… - Annals of …, 2023 - Wiley Online Library
Objective The objective of this study was to analyze the evolution of alpha and beta‐CGRP
circulating levels throughout CGRP monoclonal antibodies (mAbs) treatment in patients with …

CGRP and migraine: what have we learned from measuring CGRP in migraine patients so far?

K Kamm - Frontiers in neurology, 2022 - frontiersin.org
The multi-functional neuropeptide calcitonin gene-related peptide (CGRP) plays a major
role in the pathophysiology of migraine. The detection of elevated CGRP levels during acute …

Plasma calcitonin gene-related peptide concentration is comparable to control group among migraineurs and tension type headache subjects during inter-ictal period

R Gupta, T Ahmed, B Banerjee, M Bhatia - The journal of headache and …, 2009 - Springer
Calcitonin gene-related peptide (CGRP) is known to increase during acute attack of
migraine and tension type headache (TTH). However, its concentration during inter-ictal …

Plasma calcitonin gene-related peptide: a potential biomarker for diagnosis and therapeutic responses in pediatric migraine

PC Fan, PH Kuo, MT Lee, SH Chang… - Frontiers in …, 2019 - frontiersin.org
Background: Plasma calcitonin gene-related peptide (CGRP) plays a key role in the
migraine pathophysiology. This study aimed to investigate its role in predicting diagnosis …

CGRP may play a causative role in migraine

LH Lassen, PA Haderslev, VB Jacobsen… - …, 2002 - journals.sagepub.com
Calcitonin gene-related peptide (CGRP) has been detected in increased amounts in
external jugular venous blood during migraine attacks. However, it is unknown whether this …

Evidence for increased plasma levels of calcitonin gene-related peptide in migraine outside of attacks

M Ashina, L Bendtsen, R Jensen, S Schifter, J Olesen - Pain, 2000 - journals.lww.com
Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular
venous blood of adult migraineurs during acute migraine attacks, it remains unknown …

Calcitonin gene-related peptide causes migraine aura

HM Al-Khazali, H Ashina, A Wiggers, K Rose… - The Journal of …, 2023 - Springer
Background Although the involvement of calcitonin gene-related peptide (CGRP) in
migraines is well-established, its specific role in investigating the aura phase, which often …