Stability of the blood eosinophilic phenotype in stable and exacerbated COPD

DM Schumann, M Tamm, K Kostikas, D Stolz - Chest, 2019 - Elsevier
Background There is controversy regarding the use of blood eosinophil levels as a
biomarker of exacerbation risk and responsiveness of patients to inhaled corticosteroids …

Change in blood eosinophils following treatment with inhaled corticosteroids may predict long-term clinical response in COPD

AG Mathioudakis, A Bikov, P Foden… - European …, 2020 - Eur Respiratory Soc
There is an emerging role for blood eosinophil count (EOS) as a biomarker to guide inhaled
corticosteroid (ICS) therapy in COPD. Since ICS administration could influence EOS, we …

Blood eosinophil counts in COPD patients compared to controls

U Kolsum, T Southworth, N Jackson… - European Respiratory …, 2019 - Eur Respiratory Soc
In patients with COPD, blood eosinophil counts can predict the effects of inhaled
corticosteroids (ICS) on exacerbation rates [1–4]. Blood eosinophil counts are now …

Stability of blood eosinophils in patients with chronic obstructive pulmonary disease and in control subjects, and the impact of sex, age, smoking, and baseline counts

OA Oshagbemi, AM Burden, DCW Braeken… - American journal of …, 2017 - atsjournals.org
Reduction of the future risk of exacerbations represents one of the major aims in the
management of chronic obstructive pulmonary disease (COPD)(1). Although inhaled …

Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids

SH Siddiqui, ID Pavord, NC Barnes… - … journal of chronic …, 2018 - Taylor & Francis
Background Growing evidence suggests that blood eosinophil count is associated with
patient responsiveness to inhaled corticosteroids (ICS). We performed post hoc predictive …

Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD

NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Blood eosinophil levels as a biomarker in COPD

G Brusselle, ID Pavord, S Landis, S Pascoe, S Lettis… - Respiratory …, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …

The stability of blood Eosinophils in chronic obstructive pulmonary disease

GH Long, T Southworth, U Kolsum, GC Donaldson… - Respiratory …, 2020 - Springer
Blood eosinophils are a predictive biomarker of inhaled corticosteroid response in chronic
obstructive pulmonary disease (COPD). We investigated blood eosinophil stability over 1 …

[HTML][HTML] Blood eosinophil counts in chronic obstructive pulmonary disease: a biomarker of inhaled corticosteroid effects

D Singh - Tuberculosis and respiratory diseases, 2020 - ncbi.nlm.nih.gov
Blood eosinophil counts have emerged as a chronic obstructive pulmonary disease (COPD)
biomarker that predict the effects of inhaled corticosteroids (ICS) in clinical practice. Post-hoc …