Background: Due to the increasing need for kidney donors, transplantation from non-heart-
beating donors (NHBD) is currently being practiced more extensively. As detailed studies on …

Kidneys recovered from donation after cardiac death (DCD) are increasingly used to enlarge
the deceased donor pool. Such renal grafts, especially those derived from uncontrolled …

With increasing demands for 'less than ideal'kidneys for transplantation, machine perfusion
of kidneys has been utilized to improve the preservation of kidneys during storage …

Cold preservation has greatly facilitated the use of cadaveric kidneys for renal
transplantation, but, clearly, damage occurs during both the preservation episode and the …

Protection of endothelial cell function may explain the benefits of nonoxygenated
hypothermic machine perfusion (MP) for marginal kidney preservation. However, this …

Normothermic machine perfusion (NMP) of kidney grafts is a promising new preservation
method to improve graft quality and clinical outcome. Routinely, kidneys are washed out of …

The primary objective of organ preservation is to deliver a viable graft with minimal risk of
impaired postoperative graft function. In current clinical practice, preservation of transplanted …

Background. Ischemia reperfusion injury (I/R) leads to delayed graft function and remains an
important problem in renal transplantation. The aim of this experimental study was to assess …

Ischemia‐reperfusion (IR) injury is unavoidable during organ transplantation and impacts
graft quality. New paradigms are emerging including preservation at higher temperature …

Background: The isolated perfused porcine kidney (IPPK) model has been the method of
choice for the early preclinical evaluation of kidney graft preservation techniques. The …