[HTML][HTML] Neuroprotective effects of pomegranate (Punica granatum L.) juice and seed extract in paraquat-induced mouse model of Parkinson's disease

SM Fathy, HA El-Dash, NI Said - BMC Complementary Medicine and …, 2021 - Springer
Abstract Background Paraquat,(PQ), an herbicide that can induce Parkinsonian-like
symptoms in rodents and humans. The consumption of phytochemical-rich plants can …

Hesperidin protects against behavioral alterations and loss of dopaminergic neurons in 6-OHDA-lesioned mice: the role of mitochondrial dysfunction and apoptosis

MS Antunes, FVL Ladd, AABL Ladd, AL Moreira… - Metabolic Brain …, 2021 - Springer
Hesperidin is a flavonoid glycoside that is frequently found in citrus fruits. Our group have
demonstrated that hesperidin has neuroprotective effect in 6-hydroxydopamine (6-OHDA) …

Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms

M Iranshahy, B Javadi, A Sahebkar - Phytotherapy research, 2022 - Wiley Online Library
Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

Effect of quercetin and its glucuronide metabolite upon 6-hydorxydopamine-induced oxidative damage in Neuro-2a cells

R Mukai, K Kawabata, S Otsuka, A Ishisaka… - Free radical …, 2012 - Taylor & Francis
Quercetin is ubiquitously distributed in plant foods. This antioxidative polyphenol is mostly
converted to conjugated metabolites in the body. Parkinson disease (PD) has been …

[HTML][HTML] Lycopodium attenuates loss of dopaminergic neurons by suppressing oxidative stress and neuroinflammation in a rat model of Parkinson's disease

RL Jayaraj, R Beiram, S Azimullah, MFN Meeran… - Molecules, 2019 - mdpi.com
Parkinson's disease, a chronic, age related neurodegenerative disorder, is characterized by
a progressive loss of nigrostriatal dopaminergic neurons. Several studies have proven that …

Neuroprotection of resveratrol against neurotoxicity induced by methamphetamine in mouse mesencephalic dopaminergic neurons

D Sun, Q Yue, W Guo, T Li, J Zhang, G Li, Z Liu… - Biofactors, 2015 - Wiley Online Library
Resveratrol is originally extracted from huzhang, a Chinese herbal medicine. Recently,
resveratrol has attracted a great of attention due to its antioxidant and antiapoptotic …

Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a …

J Wang, C Tang, MG Ferruzzi, B Gong… - Molecular nutrition & …, 2013 - Wiley Online Library
Scope Metabolic syndrome has become an epidemic and poses tremendous burden on the
health system. People with metabolic syndrome are more likely to experience cognitive …

Punicalagin reduces H2O2-induced cytotoxicity and apoptosis in PC12 cells by modulating the levels of reactive oxygen species

ME Clementi, G Pani, B Sampaolese… - Nutritional …, 2018 - Taylor & Francis
Background: Oxidative stress has long been linked to neuronal cell death in many
neurodegenerative diseases. Antioxidant conventional supplements are poorly effective in …

[HTML][HTML] 6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation

G Park, HG Kim, MS Ju, SK Ha, Y Park… - Acta Pharmacologica …, 2013 - nature.com
Aim: 6-Shogaol [1-(4-hydroxy-methoxyphenyl)-4-decen-one], a pungent compound isolated
from ginger, has shown various neurobiological and anti-inflammatory effects. The aim of …

Protective effect of Nrf2–ARE activator isolated from green perilla leaves on dopaminergic neuronal loss in a Parkinson's disease model

Y Masaki, Y Izumi, A Matsumura, A Akaike… - European journal of …, 2017 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder characterized by a selective loss
of dopaminergic neurons in the substantia nigra (SN), and oxidative stress is thought to …