[HTML][HTML] Hypotensive effect of captopril on deoxycorticosterone acetate-salt-induced hypertensive rat is associated with gut microbiota alteration

H Wu, TYC Lam, TF Shum, TY Tsai, J Chiou - Hypertension Research, 2022 - nature.com
The role of the gut microbiota in various metabolic diseases has been widely studied. This
study aims to test the hypothesis that gut microbiota dysbiosis is associated with DOCA-salt …

[HTML][HTML] Effects of losartan, atorvastatin, and aspirin on blood pressure and gut microbiota in spontaneously hypertensive rats

S Dong, Q Liu, X Zhou, Y Zhao, K Yang, L Li, D Zhu - Molecules, 2023 - mdpi.com
Many studies have shown that alterations in the gut microbiota are associated with
hypertension. Our study aimed to observe the characteristics of the gut microbiota in …

[HTML][HTML] Mycophenolate improves brain–gut Axis inducing remodeling of gut microbiota in DOCA-salt hypertensive rats

I Robles-Vera, N de la Visitación, M Sánchez… - Antioxidants, 2020 - mdpi.com
Microbiota is involved in the host blood pressure (BP) regulation. The immunosuppressive
drug mofetil mycophenolate (MMF) ameliorates hypertension. The present study analyzed …

[HTML][HTML] Mineralocorticoid receptor blockade improved gut microbiota dysbiosis by reducing gut sympathetic tone in spontaneously hypertensive rats

C González-Correa, J Moleón, S Miñano… - Biomedicine & …, 2023 - Elsevier
Microbiota has a crucial role in the host blood pressure (BP) regulation. The present study
analyzes whether the mineralocorticoid receptor antagonist spironolactone ameliorates the …

Sustained captopril‐induced reduction in blood pressure is associated with alterations in gut‐brain axis in the spontaneously hypertensive rat

T Yang, V Aquino, GO Lobaton, H Li… - Journal of the …, 2019 - Am Heart Assoc
Background We have demonstrated that the antihypertensive effect of the angiotensin‐
converting enzyme inhibitor, captopril (CAP), is associated with beneficial effects on gut …

Depletion of the gut microbiota enhances the blood pressure-lowering effect of captopril: implication of the gut microbiota in resistant hypertension

J Kyoung, T Yang - Hypertension Research, 2022 - nature.com
The role of the gut microbiota in the initiation and progression of hypertension has been
newly identified, suggesting that targeting the gut microbiota may provide a new treatment …

The role of gut microbiota in hypertension pathogenesis and the efficacy of antihypertensive drugs

Y Xiong, Y Xiong, P Zhu, Y Wang, H Yang… - Current hypertension …, 2021 - Springer
Abstract Purpose of Heading To review the relationship between intestinal microbes and
hypertension and its impact on the efficacy of antihypertensive drugs, and help to address …

Gut microbiota and hypertension: association, mechanisms and treatment

Z Yang, Q Wang, Y Liu, L Wang, Z Ge, Z Li… - Clinical and …, 2023 - Taylor & Francis
Objectives Hypertension is one of the most important risk factors for cardio-cerebral vascular
diseases, which brings a heavy economic burden to society and becomes a major public …

[HTML][HTML] Genetically determined hypertensive phenotype affects gut microbiota composition, but not vice versa

P Konopelski, M Konop, K Perlejewski… - Journal of …, 2021 - journals.lww.com
Objectives: Research suggests reciprocal crosstalk between the host and gut bacteria. This
study evaluated the interaction between gut microbiota and arterial blood pressure (BP) in …

Gut microbiota modulates stress-induced hypertension through the HPA axis

Q Wu, Z Xu, S Song, H Zhang, W Zhang, L Liu… - Brain Research …, 2020 - Elsevier
Stress is associated with an increased risk of hypertension, and the incidence of stress-
related hypertension has risen rapidly in recent years; however, the underlying mechanisms …