Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of …

EJ Koh, KJ Kim, JH Song, J Choi, HY Lee… - International Journal of …, 2017 - mdpi.com
Spirulina maxima, a microalga containing high levels of protein and many polyphenols,
including chlorophyll a and C-phycocyanin, has antioxidant and anti-inflammatory …

Spirulina maxima extract prevents cell death through BDNF activation against amyloid beta 1-42 (Aβ1-42) induced neurotoxicity in PC12 cells

EJ Koh, KJ Kim, J Choi, DH Kang, BY Lee - Neuroscience letters, 2018 - Elsevier
Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60–
70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce …

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

EJ Koh, YJ Seo, J Choi, HY Lee, DH Kang, KJ Kim… - Molecules, 2017 - mdpi.com
Spirulina maxima is a microalgae which contains flavonoids and other polyphenols.
Although Spirulina maxima 70% ethanol extract (SM70EE) has diverse beneficial effects, its …

Spirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated mice

JH Hwang, IT Lee, KC Jeng, MF Wang… - Journal of nutritional …, 2011 - jstage.jst.go.jp
Spirulina has proven to be effective in treating certain cancers, hyperlipidemia,
immunodeficiency, and inflammatory processes. In this study, we aimed to investigate the …

Effect of Fermented Spirulina maxima Extract on Cognitive‐Enhancing Activities in Mice with Scopolamine‐Induced Dementia

WY Choi, DH Kang, HY Lee - Evidence‐Based Complementary …, 2018 - Wiley Online Library
This work provides the first demonstration that Spirulina maxima extract fermented with the
lactic acid bacterium Lactobacillus planetarium HY‐08 has the ability to ameliorate …

Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia

A Piovan, J Battaglia, R Filippini… - Frontiers in …, 2021 - frontiersin.org
Background: Uncontrolled neuroinflammation and microglia activation lead to cellular and
tissue damage contributing to neurodegenerative and neurological disorders. Spirulina …

Beneficial effects of spirulina consumption on brain health

T Trotta, C Porro, A Cianciulli, MA Panaro - Nutrients, 2022 - mdpi.com
Spirulina is a microscopic, filamentous cyanobacterium that grows in alkaline water bodies.
It is extensively utilized as a nutraceutical food supplement all over the world due to its high …

Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia

EL Ngu, CY Tan, NJY Lai, KH Wong, SH Lim, LC Ming… - Metabolites, 2022 - mdpi.com
The disease burden of neurodegenerative diseases is on the rise due to the aging
population, and neuroinflammation is one of the underlying causes. Spirulina platensis is a …

Neuroprotective effect of Spirulina in cerebral ischemia–reperfusion injury in rats

S Thaakur, R Sravanthi - Journal of neural transmission, 2010 - Springer
Epidemiological studies indicate that the intake of Mediterranean-style diet is inversely
associated with risk of stroke, cardiovascular diseases, and cancer. Spirulina is widely used …

Enhancement of the Neuroprotective Effect of Fermented Spirulina maxima Associated with Antioxidant Activities by Ultrasonic Extraction

WY Choi, DH Kang, SJ Heo, HY Lee - Applied Sciences, 2018 - mdpi.com
This study is the first demonstration of the neuroprotective activity of the marine alga,
Spirulina maxima, fermented by Lactobacillus plantarum HY-08, which was freshly isolated …