Background Schistosomiasis is a disease of major public health importance in sub-Saharan
Africa. Immunoregulation begins early in schistosome infection and is characterized by …

Schistosomiasis is a disease caused by parasitic flatworms of the Schistosoma spp., and is
increasingly recognized to alter the immune system, and the potential to respond to …

Background Improved helminth control is required to alleviate the global burden of
schistosomiasis and schistosome-associated pathologies. Current control efforts rely on the …

While antigens from Schistosoma schistosomula have been suggested as potential vaccine
candidates, the association between antibody responses with schistosomula antigens and …

A number of different schistosome antigens are capable of partially protecting experimental
animals from challenge infection. More than 100 such antigens have been identified, about …

Schistosomiasis is a debilitating helminthiasis which commonly establishes as a chronic
infection in people from endemic areas. As a potent modulator of the host immune response …

Few studies comparing schistosomiasis vaccine candidate antigens between laboratories
have been carried out and published. Generally, only the investigators who discovered the …

Despite mass drug administration programmes with praziquantel, the prevalence of
schistosomiasis remains high. A vaccine is urgently needed to control transmission of this …

Field trials of new schistosomiasis vaccines are anticipated within the next few years, but
there remains great uncertainty regarding the optimal design of vaccination programmes …

We examined associations between schistosome‐specific antibody responses and
reinfection in Senegalese individuals recently exposed to Schistosoma mansoni. The effects …