Schizophrenia is a highly heritable mental disorder characterized by functional
dysconnectivity across the brain. However, the relationships between polygenic risk factors …

BackgroundSchizophrenia is a complex mental disorder with high heritability and polygenic
inheritance. Multimodal neuroimaging studies have also indicated that abnormalities of …

Schizophrenia is a highly heritable psychiatric disorder characterized by widespread
functional and structural brain abnormalities. However, previous association studies …

Alterations of connectivity are central to the systems-level pathophysiology of schizophrenia.
One of the best-established genome-wide significant risk variants for this highly heritable …

Recently, deriving candidate endophenotypes from brain imaging data has become a
valuable approach to study genetic influences on schizophrenia (SZ), whose …

Psychiatry is undergoing a paradigm shift from the acceptance of distinct diagnoses to a
representation of psychiatric illness that crosses diagnostic boundaries. How this transition …

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies
(GWAS) have identified multiple loci that influence the risk of developing schizophrenia …

Background Polygenicity and genetic heterogeneity pose great challenges for studying
psychiatric conditions. Genetically informed approaches have been implemented in …

Background Schizophrenia is a complex polygenic disorder with subtle, distributed
abnormalities in brain morphology. There are indications of shared genetic architecture …

The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …