Blood pressure variability and medial temporal atrophy in apolipoprotein ϵ4 carriers

IJ Sible, DA Nation… - Brain imaging and …, 2022 - Springer
Blood pressure variability is an emerging risk factor for dementia but relationships with
markers of neurodegeneration and Alzheimer's disease risk are understudied. We …

Visit-to-visit blood pressure variability and CSF Alzheimer disease biomarkers in cognitively unimpaired and mildly impaired older adults

IJ Sible, DA Nation… - Neurology, 2022 - AAN Enterprises
Background and Objectives Blood pressure variability is an emerging risk factor for cognitive
decline and dementia, but mechanisms remain unclear. The current study examined …

Visit-to-visit blood pressure variability and longitudinal tau accumulation in older adults

IJ Sible, DA Nation - Hypertension, 2022 - Am Heart Assoc
Background: Elevated blood pressure variability (BPV) is predictive of dementia,
independent of average blood pressure levels, but neuropathological mechanisms remain …

Long-term blood pressure variability across the clinical and biomarker spectrum of Alzheimer's disease

IJ Sible, DA Nation… - Journal of …, 2020 - content.iospress.com
Background: Elevated blood pressure is linked to cognitive impairment and Alzheimer's
disease (AD) biomarker abnormality. However, blood pressure levels vary over time. Less is …

Blood pressure variability and plasma Alzheimer's disease biomarkers in older adults

IJ Sible, B Yew, JY Jang, JPM Alitin, Y Li, A Gaubert… - Scientific reports, 2022 - nature.com
Blood pressure variability is an emerging risk factor for Alzheimer's disease in older adults,
independent of average blood pressure levels. Growing evidence suggests increased blood …

Visit-to-visit blood pressure variability and regional cerebral perfusion decline in older adults

IJ Sible, B Yew, S Dutt, KJ Bangen, Y Li, DA Nation… - Neurobiology of …, 2021 - Elsevier
Blood pressure variability (BPV) is linked to dementia risk, possibly through cerebral
hypoperfusion. We investigated BPV over 1 year and concurrent regional cerebral perfusion …

Blood pressure and risk of incident Alzheimer's disease dementia by antihypertensive medications and APOE ε4 allele

KB Rajan, LL Barnes, RS Wilson, J Weuve… - Annals of …, 2018 - Wiley Online Library
Objective To examine the association of blood pressure (BP) with incident Alzheimer's
disease (AD) dementia. Methods This work is based on a longitudinal, cohort study of 18 …

Atherosclerosis and Hippocampal Volumes in Older Adults: The Role of Age and Blood Pressure

A Kapasi, AW Capuano, M Lamar… - Journal of the …, 2024 - Am Heart Assoc
Background Lower hippocampal volume is associated with late‐life cognitive decline and is
an important, but nonspecific marker for clinical Alzheimer's dementia. Cerebrovascular …

Blood pressure variability predicts cognitive decline in Alzheimer's disease patients

S Lattanzi, S Luzzi, L Provinciali, M Silvestrini - Neurobiology of aging, 2014 - Elsevier
The aim of our study was to evaluate whether blood pressure variability influences the rate
of cognitive decline in Alzheimer's disease (AD). Two hundred and forty AD patients were …

Systolic Blood Pressure Is Associated with Increased Brain Amyloid Load in Mild Cognitively Impaired Participants: Alzheimer's Disease Neuroimaging Initiatives …

TV Fungwe, JS Ngwa, SP Johnson, JV Turner… - Dementia and geriatric …, 2023 - karger.com
Abstract Background: Cardiovascular disease (CVD), including elevated blood pressure
(BP), is known to promote Alzheimer's disease (AD) risk. Although brain amyloid load is a …