The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

Host defense peptides (often called cationic antimicrobial peptides) have pleiotropic
immunomodulatory functions. The human host defense peptide LL-37 is up-regulated at …

Here, we demonstrate the self-assembly of the antimicrobial human LL-37 active core
(residues 17–29) into a protein fibril of densely packed helices. The surface of the fibril …

The role of LL-37, a human cationic antimicrobial peptide, in the immune system is not yet
clearly understood. It is a widely expressed peptide that can be up-regulated during an …

[Frontiers in Bioscience 13, 3760-3767, May 1, 2008] 3760 The role of the multifunctional
peptide LL-37 in host defense Ylva Ka Page 1 [Frontiers in Bioscience 13, 3760-3767, May 1 …

The antimicrobial peptide LL-37 belongs to the cathelicidin family and is the first
amphipathic α-helical peptide isolated from human. LL-37 is considered to play an important …

Covering: up to June 2009LL-37 is a human host defence peptide that has a wide range of
biological functions, including antimicrobial and immunomodulatory properties. This review …

Abstract Treatment of Staphylococcus aureus infections continues to be a challenge due to
antimicrobial resistance. Endogenous antimicrobial peptides may offer a new option for …

Antimicrobial peptide LL-37 plays an important role in human body's first line of defense
against infection. To better understand the mechanism of action, it is critical to elucidate the …

Acinetobacter baumannii infections are difficult to treat due to multidrug resistance. Biofilm
formation by A. baumannii is an additional factor in its ability to resist antimicrobial therapy …