Importance Small vessel cerebrovascular disease, visualized as white matter
hyperintensities (WMH), is associated with cognitive decline and risk of clinical Alzheimer …

Accumulating evidence implicates small vessel cerebrovascular disease, visualized as
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …

Background: The association of white matter hyperintensities (WMH) with age-related
vascular and neurodegenerative pathologies remains incompletely understood. Objective …

Background Longitudinal investigations are needed to improve understanding of the
contributions of cerebral small vessel disease to the clinical manifestation of Alzheimer's …

White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel
disease (SVD) markers and are associated with cognitive decline, although they do not fully …

We aimed to explore the role of white matter hyperintensities (WMH) in progression of
cerebral small vessel disease (CSVD) in an urban community in China over a period of 7 …

Background New-onset Alzheimer disease (AD) is often attributed to degenerative changes
in the hippocampus. However, the contribution of regionally distributed small vessel …

Background White matter hyperintensities (WMH) of presumed vascular origin have been
associated with an increased risk of Alzheimer's disease (AD). This study aims to describe …

Although white matter hyperintensities (WMH), markers of cerebral small vessel disease
(SVD), are believed to generally increase over time, some studies have shown sharp …

Introduction It is unclear whether white matter hyperintensities (WMHs), magnetic resonance
imaging markers of small-vessel cerebrovascular disease, promote neurodegeneration and …