Abstract Glycogen synthase kinase-3 (GSK-3) is a highly conserved and multifunctional
serine/threonine protein kinase widely distributed in eukaryotic cells. GSK-3 is originally …

Abstract Glycogen synthase kinase 3 (GSK-3) is a highly conserved protein serine/threonine
kinase that plays a central role in a wide variety of cellular processes to coordinate catabolic …

Neurodegenerative diseases (NDDs) pose an increasingly prevalent threat to the well-being
and survival of elderly individuals worldwide. NDDs include Alzheimer's disease (AD) …

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) is involved in a broad
range of cellular processes including cell proliferation, apoptosis and inflammation. It is now …

Glycogen synthase kinase-3β (GSK3β) is highly abundant in the brain. Various biochemical
analyses have indicated that GSK3β is localized to different intracellular compartments …

J. Neurochem.(2010) 115, 974–983. Abstract Mammalian glycogen synthase kinase‐3
(GSK3) is generated from two genes, GSK3α and GSK3β, while a splice variant of GSK3β …

Glycogen synthase kinase-3 (GSK-3) exists as two structurally similar isoforms, α and β,
whose activities are negatively regulated by serine phosphorylation but positively controlled …

As a constitutively active kinase, glycogen synthase kinase 3 (GSK3) is a kinase which
regulates body metabolism by phosphorylation of glycogen synthase (GS) and other …

The biological activity of the enzyme glycogen synthase kinase-3 (GSK3) is fulfilled by two
paralogs named GSK3α and GSK3β, which possess both redundancy and specific …

Glycogen synthase kinase-3 (GSK-3) isoforms, GSK-3α and GSK-3β, are serine/threonine
kinases involved in numerous cellular processes and diverse diseases, including Alzheimer …