Gefitinib (GET) is a revolutionary targeted treatment inhibiting the epidermal growth factor
receptor's tyrosine kinase action by competitively inhibiting the ATP binding site. In …

The zeolitic imidazole framework (ZIF) is a novel metal-organic framework with distinctive
properties, including crystalline form, controllable pore size, wide surface area and …

ABSTRACT A simple and cost-effective synthesis method for zeolitic imidazolate framework-
8 (ZIF-8) was developed and loaded with metformin (MET@ ZIF-8) for pH sensitive-release …

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (GEF) has
been used to treat nonsmall-cell lung cancer (NSCLC); yet, the curative effect of GEF was …

A novel pH-responsive drug carrier for the delivery of specific Docetaxel (DTX)
administration is developed based on a zeolitic imidazolate framework (ZIF-8). Aminating …

Abstract Zinc (zeolitic) imidazolate framework 8 (ZIF-8) has been widely considered in the
literature as an ideal candidate for drug delivery especially anti-cancer drugs. However, the …

Zeolitic imidazole frameworks (ZIFs), which combine the favorable characteristics of tunable
porosity, controlled structure, and facile functionalization, are explored as a novel class of …

Glioma cancer is the primary cause of cancer-related fatalities globally for both men and
women. Traditional chemotherapy treatments for this condition frequently result in reduced …

Zeolitic imidazole frame work, a special class of porous crystalline material with tunable pore
size has emerged as a promising candidate for biomedical applications. The present work …

Dihydromyricetin (DHM) has garnered attention due to its promising antitumor activity, but its
low bioavailability restricts its clinical application. Thus, developing nano-drug delivery …