The basal forebrain cholinergic neurons (BFCN) provide the primary source of cholinergic
innervation of the human cerebral cortex. They are involved in the cognitive processes of …

Basal forebrain cholinergic neurons (BFCN) are selectively vulnerable in Alzheimer's
disease (AD). We have shown that most of the BFCN in the human brain contain the calcium …

The basal forebrain cholinergic system (BFCS) has long been implicated in age-related
cognitive changes and the pathophysiology of Alzheimer's disease (AD). Limitations of …

Evidence suggests that the basal forebrain (BF) cholinergic system degenerates early in the
course of Alzheimer's disease (AD), likely due to the vulnerability of BF cholinergic neurons …

Tau is a microtubule-associated protein that forms neurofibrillary tangles (NFTs) in the
selective vulnerable long projection neurons of the cholinergic basal forebrain (CBF) in …

Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary financial and emotional burdens (Apostolova …

Alzheimer's disease (AD) is the most common form of degenerative dementia and is
characterized by progressive impairment in cognitive function during mid-to late-adult life …

Cholinergic neurons of the basal forebrain (BFCN) are selectively vulnerable in
neurodegenerative disorders of the elderly, particularly in Alzheimer's disease (AD). We …

The cholinergic neurons of the basal forebrain (BF) provide virtually all of the brain's cortical
and amygdalar cholinergic input. They are particularly vulnerable to neuropathology in early …

Acetylcholine is widely distributed in the nervous system and has been implicated to play a
critical role in cerebral cortical development, cortical activity, controlling cerebral blood flow …