Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future

J Wintrich, I Kindermann, C Ukena, S Selejan… - Clinical Research in …, 2020 - Springer
In contrast to the wealth of proven therapies for heart failure with reduced ejection fraction
(HFrEF), therapeutic efforts in the past have failed to improve outcomes in heart failure with …

New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes

M Senni, WJ Paulus, A Gavazzi, AG Fraser… - European heart …, 2014 - academic.oup.com
The management of heart failure with reduced ejection fraction (HF-REF) has improved
significantly over the last two decades. In contrast, little or no progress has been made in …

Diagnosis and management of heart failure with preserved ejection fraction: 10 key lessons

A Afsin Oktay, SJ Shah - Current cardiology reviews, 2015 - ingentaconnect.com
Heart failure with preserved ejection fraction (HFpEF) is a common clinical syndrome
associated with high rates of morbidity and mortality. Due to the lack of evidence-based …

Treatment of heart failure with preserved ejection fraction

AM Ilieșiu, AS Hodorogea - Heart Failure: From Research to Clinical …, 2018 - Springer
Heart failure with preserved ejection fraction (HFpEF) is a growing epidemiologic problem
affecting more than half of the patients with heart failure (HF). HFpEF has a significant …

The pathophysiology of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

How to manage heart failure with preserved ejection fraction: practical guidance for clinicians

AS Desai, CSP Lam, JJV McMurray, MM Redfield - Heart failure, 2023 - jacc.org
Although patients with heart failure with preserved ejection fraction (HFpEF)(left ventricular
ejection fraction≥ 50%) comprise nearly half of those with chronic heart failure, evidence …

Developing therapies for heart failure with preserved ejection fraction: current state and future directions

J Butler, GC Fonarow, MR Zile, CS Lam, L Roessig… - JACC: Heart Failure, 2014 - jacc.org
The burden of heart failure with preserved ejection fraction (HFpEF) is considerable and is
projected to worsen. To date, there are no approved therapies available for reducing …

Understanding heart failure with preserved ejection fraction: where are we today?

L Van Heerebeek, WJ Paulus - Netherlands Heart Journal, 2016 - Springer
Heart failure with preserved ejection fraction (HFpEF) represents a complex and
heterogeneous clinical syndrome, which is increasingly prevalent and associated with poor …

Heart failure with preserved ejection fraction diagnosis and treatment: an updated review of the evidence

MG Del Buono, G Iannaccone, R Scacciavillani… - Progress in …, 2020 - Elsevier
Over the last several decades, clinicians and clinical scientists have had growing interest in
heart failure (HF) diagnosis and treatment. While HF with reduced ejection fraction (EF) is a …