Epigenetic regulation of bone remodeling and its impacts in osteoporosis
Epigenetics describes mechanisms which control gene expression and cellular processes
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …
The role of epigenomics in osteoporosis and osteoporotic vertebral fracture
Osteoporosis is a complex multifactorial condition of the musculoskeletal system.
Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical …
Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical …
Epigenetic mechanisms of bone regeneration and homeostasis
Y Liu, XL Zhang, L Chen, X Lin, D Xiong, F Xu… - Progress in Biophysics …, 2016 - Elsevier
Bone regeneration is a promising avenue for osteoporosis (OP) treatment. It consists of
several procedures, such as the osteogenic differentiation of mesenchymal stem cells as …
several procedures, such as the osteogenic differentiation of mesenchymal stem cells as …
The roles of epigenetics regulation in bone metabolism and osteoporosis
F Xu, W Li, X Yang, L Na, L Chen, G Liu - Frontiers in cell and …, 2021 - frontiersin.org
Osteoporosis is a metabolic disease characterized by decreased bone mineral density and
the destruction of bone microstructure, which can lead to increased bone fragility and risk of …
the destruction of bone microstructure, which can lead to increased bone fragility and risk of …
Do epigenetic marks govern bone mass and homeostasis?
J Delgado-Calle, P Garmilla, JA Riancho - Current genomics, 2012 - ingentaconnect.com
Bone is a specialized connective tissue with a calcified extracellular matrix in which cells are
embedded. Besides providing the internal support of the body and protection for vital …
embedded. Besides providing the internal support of the body and protection for vital …
Epigenetic mechanisms in bone biology and osteoporosis: can they drive therapeutic choices?
F Marini, L Cianferotti, ML Brandi - International journal of molecular …, 2016 - mdpi.com
Osteoporosis is a complex multifactorial disorder of the skeleton. Genetic factors are
important in determining peak bone mass and structure, as well as the predisposition to …
important in determining peak bone mass and structure, as well as the predisposition to …
New insights into the epigenetics of osteoporosis
JG Letarouilly, O Broux, A Clabaut - Genomics, 2019 - Elsevier
Osteoporosis is characterized by reduced bone formation and accumulation of adipocytes in
the bone marrow compartment. The decrease in bone mass results from an imbalance …
the bone marrow compartment. The decrease in bone mass results from an imbalance …
Epigenetic regulation of bone cells
KH Park-Min - Connective tissue research, 2017 - Taylor & Francis
Bone is a major organ in the skeletal system that supports and protects muscles and other
organs, facilitates movement and hematopoiesis, and forms a reservoir of minerals including …
organs, facilitates movement and hematopoiesis, and forms a reservoir of minerals including …
Epigenetics and bone remodeling
A Husain, MA Jeffries - Current osteoporosis reports, 2017 - Springer
Abstract Purpose of Review Bone remodeling is a diverse field of study with many direct
clinical applications; past studies have implicated epigenetic alterations as key factors of …
clinical applications; past studies have implicated epigenetic alterations as key factors of …
Molecular and genetic mechanisms of osteoporosis: implication for treatment
Osteoporosis is a leading public health problem in our rapidly growing, aging population. It
is characterized by reduced bone mass and microarchitectural deterioration of bone tissue …
is characterized by reduced bone mass and microarchitectural deterioration of bone tissue …