Osteoporosis is well known to be a poly-factorial skeletal disorder characterized by a low
bone mineral density (BMD) at which the risk of developing fracture is remarkably increased …

Phenotypic variation in skeletal traits and diseases is the product of genetic and
environmental factors. Epigenetic mechanisms include information‐containing factors, other …

Genomic technologies have evolved rapidly contributing to the understanding of diseases.
Genome-wide association studies (GWAS) and whole-exome sequencing have aided the …

Osteoporosis is a systemic degenerative bone disease characterized by low bone mass and
damage to bone microarchitecture, which increases bone fragility and susceptibility to …

Introduction Osteoporosis is a common disease characterised by low bone mineral density
and an increased risk of fragility fractures. Methods We conducted a literature review of …

Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

In the past few years, our molecular understanding of bone formation has continued to
increase. This review aims to present a comprehensive view of the current state of …

Objectives Osteoporosis is a chronic disease. The aim of this study was to identify key genes
in osteoporosis. Methods Microarray data sets GSE56815 and GSE56814, comprising 67 …

Both genetic and environmental factors are involved in the pathogenesis of osteoporosis
and other skeletal disorders. Epidemiological studies have revealed an influence of a variety …

Bone is a dynamic tissue in constant change; maintenance of bone mass throughout life
relies on the bone remodeling process, which continually replaces old and damaged bone …