Ensoma is poised to create a new therapeutic category. Leveraging first-in-class delivery
and engineering, the biotech aims to harness the power of hematopoietic stem cells (HSCs) …

Cell-type-specific in vivo delivery of genome editing molecules is the next breakthrough that
will drive biological discovery and transform the field of cell and gene therapy. Here, we …

The recently discovered CRISPR/Cas9 system is widely-used in basic research and is a
useful tool for disease modeling and gene editing therapies. However, long-term expression …

In recent years, the clustered regularly interspaced short palindromic repeats-associated
protein 9 (CRISPR-Cas9) technology that won the 2020 Nobel Prize in Chemistry has …

The CRISPR/Cas system has been developed as a potent tool for genome engineering and
transcription regulation. However, the efficiency of the delivery of the system into cells …

Replication defective lentiviruses or retroviruses are capable of stably integrating
transgenes into the genome of an infected host cell. This technique has been widely used to …

Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins
(CRISPR/Cas) have revolutionized science and medicine. However, applying the …

CRISPR-Cas9 gene editing has emerged as a powerful therapeutic technology, but the lack
of safe and efficient in vivo delivery systems, especially for tissue-specific vectors, limits its …

A recent publication in Cell describes the development and application of engineered virus-
like particles (eVLPs) that efficiently package and deliver therapeutic gene-editing proteins …