Exploitation of fibrinolytic enzymes in combating blood clotting disorders–recent advances and strategies: A comprehensive Review

SK Sahoo, S Sahoo - Advances in Pharmaceutical Biotechnology: Recent …, 2020 - Springer
Formation of blood clumps inside vessels which restrict blood circulation throughout
circulatory system is known as thrombosis. This leads to origin of numerous abnormalities …

Fibrinolytic enzyme-an overview

P Abdul Rahim, D Rengaswamy - Current pharmaceutical …, 2022 - ingentaconnect.com
Cardiovascular diseases, like coronary heart disease or artery disorders (arteriosclerosis,
including artery solidification), heart failure (myocardial infarction), arrhythmias, congestive …

[HTML][HTML] Role of fibrinolytic enzymes in anti-thrombosis therapy

F Altaf, S Wu, V Kasim - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Thrombosis, a major cause of deaths in this modern era responsible for 31% of all global
deaths reported by WHO in 2017, is due to the aggregation of fibrin in blood vessels which …

Thrombolytic enzymes of microbial origin: a review

D Diwan, Z Usmani, M Sharma, JW Nelson… - International journal of …, 2021 - mdpi.com
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …

[PDF][PDF] An overview about fibrinolytic enzymes from microorganisms and algae: production and characterization

PEC e Silva, RP Bezerra, ALF Porto - Journal of Pharmaceutical and …, 2016 - jpabs.org
Cardiovascular diseases are the leading causes of death through the world. A common
cause of cardiovascular diseases is an abnormal clot formation, called “thrombus”. Although …

Microbial fibrinolytic enzymes as anti-thrombotics: production, characterisation and prodigious biopharmaceutical applications

C Sharma, A Osmolovskiy, R Singh - Pharmaceutics, 2021 - mdpi.com
Cardiac disorders such as acute myocardial infarction, embolism and stroke are primarily
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …

Fibrinolytic enzymes for thrombolytic therapy

SS Kumar, A Sabu - Therapeutic enzymes: function and clinical …, 2019 - Springer
Cardiovascular diseases are a group of disorders consisting importantly of coronary heart
disease, peripheral arterial disease, cerebrovascular disease, rheumatic heart disease …

Production of thrombolytic and fibrinolytic proteases: current advances and future prospective

S Ghosh, S Saha, S Sahoo - … of Enzymes in Industry, Healthcare and …, 2021 - Springer
Cardiovascular diseases are one of the leading causes of death, globally. Thrombolytic and
fibrinolytic therapies are effective treatments to dissolve the blood clots, improve the blood …

Serine-proteases as plasminogen activators in terms of fibrinolysis

M Flemmig, MF Melzig - Journal of Pharmacy and …, 2012 - academic.oup.com
Objectives This review should give an overview about the natural human plasminogen
activators and their various modified variants as well as similar substances isolated from …

[PDF][PDF] Evolutionary Trend of Thrombolytic–Their Significance

A Kumar, KK Pulicherla, KS Ram… - International Journal of …, 2011 - gvpress.com
Thrombolytic drugs have been used in the clinical arena to treat a wide variety of venous
and arterial thromboembolic disorders which are a main cause of death. Thrombolytic …