A fibrinolytic protease AfeE from Streptomyces sp. CC5, with potent thrombolytic activity in a mouse model

Z Sun, P Liu, G Cheng, B Zhang, W Dong, X Su… - International journal of …, 2016 - Elsevier
Fibrinolytic proteases have potential applications in cardiovascular disease therapy. A novel
fibrinolytic protease, AfeE, with strong thrombolytic activity was purified from Streptomyces …

Towards better thrombolytic therapy

D Collen, HR Lijnen, HK Gold - Progress in cardiovascular diseases, 1991 - Elsevier
Cardiovascular diseases are a main cause of death and disability in Western societies. They
comprise three main categories, namely coronary artery disease leading to myocardial …

[引用][C] Nattokinase enzyme; an evaluation of its cellular and potential therapeutic actions

MG Tyagi - European Journal of Pharmaceutical and Medical …, 2016

[引用][C] An overview on microbial fibrinolytic proteases

EVN Raju, G Divakar - International …, 2014 - International Journal of …

[PDF][PDF] Isolation and Characterization of Alkaline Proteases Producing Indigenous Bacillus sp. as a Source of Thrombolytic and Fibrinolytic Agents

T Akhtar, MAA Sikder, T Yeasmin… - … University Journal of …, 2023 - researchgate.net
Fibrinolytic enzymes derived from bacteria can be effective as a potent, safe and cost-
effective thrombolytic agent for the prevention and treatment of cardiovascular diseases. In …

[HTML][HTML] The role of fibrinolytic system in health and disease

HC Kwaan - International journal of molecular sciences, 2022 - mdpi.com
The fibrinolytic system is composed of the protease plasmin, its precursor plasminogen and
their respective activators, tissue-type plasminogen activator (tPA) and urokinase-type …

Development of new fibrinolytic agents

S Ueshima, O Matsuo - Current pharmaceutical design, 2006 - ingentaconnect.com
Since the activation of coagulation system and platelets triggers the thrombosis, the agents
possessing anticoagulation or anti-platelet function have been used for the antithrombotic …

[HTML][HTML] Importance of endogenous fibrinolysis in platelet thrombus formation

YX Gue, DA Gorog - International journal of molecular sciences, 2017 - mdpi.com
The processes of thrombosis and coagulation are finely regulated by endogenous
fibrinolysis maintaining healthy equilibrium. When the balance is altered in favour of platelet …

[引用][C] PRODUCTION OF FIBRINOLYTIC ENZYME (NATTOKINASE) FROM BACILLUS SP.

P Singh, R Negi, V Sharma… - Indo American …, 2018 - SSJ COLL PHARMACY-SSJCP …

[PDF][PDF] AN OVERVIEW ON MICROBIAL FIBRINOLYTIC PROTEASES.

E Venkata Naga Raju, G Divakar - International Journal of …, 2014 - researchgate.net
Microbial fibrinolytic proteases are of considerable interest in view of their specific activity
and stability at biological pH. This review describes different isolation methods which enable …