The roles of MCPyV early region in IL-17A-mediated inflammation and autophagy

J Miao - 2021 - theses.hal.science
Merkel cell carcinoma (MCC) is a rare aggressive skin malignancy that affects
predominantly elderly and immunocompromised patients. Merkel cell polyomavirus …

The MCPyV st-ag and IL33/ST2 axis: critical role in merkel cell carcinoma

K Rasheed, S Fismen, Ø Grimstad, B Sveinbjørnsson… - Cancer Research, 2019 - AACR
Abstract Merkel Cell polyomavirus (MCPyV) is a causal factor in Merkel Cell Carcinoma
(MCC). The oncogenic potential is mediated through its viral oncoproteins large T-antigen …

Connecting Viral Oncoproteins to microRNA, Autophagy and Metabolism in Merkel Cell Carcinoma

S Kumar - 2019 - search.proquest.com
Merkel cell carcinoma (MCC) is an aggressive type of skin cancer. Around 80% of MCCs
harbor an integrated Merkel cell polyomavirus (MCPyV) genome with a mutation in the large …

Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes

S Kumar, H Xie, H Shi, J Gao, CC Juhlin… - … Journal of Cancer, 2020 - Wiley Online Library
Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy
plays an important role in immune suppression and viral oncogenesis. Merkel cell …

[HTML][HTML] Merkel cell polyomavirus small T antigen promotes pro-glycolytic metabolic perturbations required for transformation

C Berrios, M Padi, MA Keibler, DE Park, V Molla… - PLoS …, 2016 - journals.plos.org
Merkel cell polyomavirus (MCPyV) is an etiological agent of Merkel cell carcinoma (MCC), a
highly aggressive skin cancer. The MCPyV small tumor antigen (ST) is required for …

[HTML][HTML] The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma

K Rasheed, U Moens, B Policastro, JI Johnsen… - International Journal of …, 2022 - mdpi.com
Merkel cell polyomavirus (MCPyV) is a causal factor in Merkel cell carcinoma (MCC). The
oncogenic potential is mediated through its viral oncoproteins large T-antigen (LT) and small …

[HTML][HTML] Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential

JF Yang, W Liu, J You - PLoS Pathogens, 2023 - journals.plos.org
Merkel cell polyomavirus (MCPyV) is associated with approximately 80% of cases of Merkel
cell carcinoma (MCC), an aggressive type of skin cancer. The incidence of MCC has tripled …

Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility

SJ Dobson, A Anene, JR Boyne, J Mankouri… - Biochemical …, 2020 - portlandpress.com
Merkel cell carcinoma (MCC) is an aggressive skin cancer with high rates of recurrence and
metastasis. Merkel cell polyomavirus (MCPyV) is associated with the majority of MCC cases …

[HTML][HTML] CCL17/TARC and CCR4 expression in Merkel cell carcinoma

K Rasheed, I Abdulsalam, S Fismen, Ø Grimstad… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine skin cancer. In
more than 80% of the cases, Merkel cell polyomavirus (MCPyV) is a causal factor. The …

Understanding the role of Merkel cell polyomavirus oncoproteins in the cellular transformation of mammalian Merkel cells

LM Knight - 2014 - etheses.whiterose.ac.uk
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer of neuroendocrine origin
with a high propensity for metastasis through the dermal lymphatic system. In 2008, Merkel …