The anti-inflammatory effect of vasoactive peptides from soybean protein hydrolysates by mediating serum extracellular vesicles-derived miRNA-19b/CYLD/TRAF6 …
T Song, M Zhou, W Li, M Lv, L Zheng, M Zhao - Food Research International, 2022 - Elsevier
The excessive accumulation of angiotensin II (Ang II) in the vascular microenvironment
promotes vascular dysfunction including vascular endothelial inflammation and remodeling …
promotes vascular dysfunction including vascular endothelial inflammation and remodeling …
[HTML][HTML] The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway
Hypertension triggers oxidative stress, causing dysfunction in organs, including the brain,
heart, and kidney. In this study, we examined the potential renal benefit of the soybean …
heart, and kidney. In this study, we examined the potential renal benefit of the soybean …
Soybean-derived antihypertensive peptide LSW (Leu–Ser–Trp) antagonizes the damage of angiotensin II to vascular endothelial cells through the trans-vesicular …
T Song, M Lv, M Zhou, M Huang… - Journal of Agricultural …, 2021 - ACS Publications
An emerging inference is that vascular cells transfer their biological cargo to recipient cells
by secretion of extracellular vesicles (EVs). This study explored the effects of EVs produced …
by secretion of extracellular vesicles (EVs). This study explored the effects of EVs produced …
Regulatory effects of a pea-derived peptide Leu-Arg-Trp (LRW) on dysfunction of rat aortic vascular smooth muscle cells against angiotensin II stimulation
Vascular oxidative stress, inflammatory response, and proliferation are crucial mediators of
vascular dysfunction which contribute to the pathology of hypertension. A tripeptide, LRW …
vascular dysfunction which contribute to the pathology of hypertension. A tripeptide, LRW …
The protective effects of tripeptides VPP and IPP against small extracellular vesicles from angiotensin II-induced vascular smooth muscle cells mediating endothelial …
T Song, M Lv, L Zhang, X Zhang, G Song… - Journal of Agricultural …, 2020 - ACS Publications
Endothelial dysfunction is a common disorder of vascular homeostasis in hypertension
characterized by oxidative stress, malignant migration, inflammatory response, and active …
characterized by oxidative stress, malignant migration, inflammatory response, and active …
Egg ovotransferrin‐derived ACE inhibitory peptide IRW increases ACE2 but decreases proinflammatory genes expression in mesenteric artery of spontaneously …
Scope Egg ovotransferrin‐derived angiotensin converting enzyme (ACE) inhibitory peptide
IRW was previously shown to reduce blood pressure in spontaneously hypertensive rats …
IRW was previously shown to reduce blood pressure in spontaneously hypertensive rats …
Tripeptide Leu-Ser-Trp regulates the vascular endothelial cells phenotype switching by mediating the vascular smooth muscle cells-derived small extracellular …
T Song, M Zhou, W Li, L Zheng, J Wu, M Zhao - Molecules, 2022 - mdpi.com
Tripeptide LSW, initially identified as a potent ACE inhibitory peptide from soybean protein,
was recently reported to exert a protective effect against angiotensin II-induced endothelial …
was recently reported to exert a protective effect against angiotensin II-induced endothelial …
Egg white–derived antihypertensive peptide IRW (Ile‐Arg‐Trp) reduces blood pressure in spontaneously hypertensive rats via the ACE2/ang (1‐7)/mas receptor Axis
Scope It is found in the previous study that egg‐white‐derived antihypertensive peptide Ile‐
Arg‐Trp (IRW) upregulated angiotensin converting enzyme 2 (ACE2) in spontaneously …
Arg‐Trp (IRW) upregulated angiotensin converting enzyme 2 (ACE2) in spontaneously …
Egg white-derived antihypertensive peptide IRW (Ile-Arg-Trp) inhibits angiotensin II-stimulated migration of vascular smooth muscle cells via angiotensin type I …
Excessive proliferation, inflammation, oxidative stress, and migration induced by angiotensin
II (Ang II), occurring in vascular smooth muscle cells (VSMCs) during vascular remodelling …
II (Ang II), occurring in vascular smooth muscle cells (VSMCs) during vascular remodelling …
Tripeptides Val-Pro-Pro (VPP) and Ile-Pro-Pro (IPP) regulate the proliferation and migration of vascular Smooth muscle cells by interfering Ang II-induced human …
T Song, M Lv, B Sun, L Zheng… - Journal of agricultural and …, 2020 - ACS Publications
Angiotensin II (Ang II), a vasoactive factor in the renin–angiotensin–aldosterone system
(RAAS), can regulate vasoconstriction and promote multiple vascular diseases. In this study …
(RAAS), can regulate vasoconstriction and promote multiple vascular diseases. In this study …