A fistula is defined as an abnormal communication between two epithelium-lined surfaces,
and fistula-in-ano consists of an abnormal tract connecting the anal canal or rectum with the …

Background: Crohn's disease (CD) is an autoimmune disease of the gastrointestinal tract,
characterized by relapsing and remitting courses. The disease is debilitating in nature with …

Crohn's Disease (CD), which usually leads to anal fistulas among patients, is the most
important inflammatory bowel disease that causes morbidity in many people around the …

Marrow-derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal
Fistulas in Patients with Crohn's Disease.” The authors present a potential new treatment …

Introduction: Complex perianal fistula continues to be a real surgical challenge due to the
high rate of recurrence and the possibility of fecal incontinence after surgery. In the case of …

Introduction Mesenchymal stem (or stromal) cells are a promising therapy for the treatment
of various inflammatory and autoimmune diseases. This study aimed to understand …

Perianal fistula in patients with Crohn's disease is an extremely challenging condition. The
disease tends to reoccur, and with current treatment options, a large number of patients are …

Although monoclonal antibodies have changed the treatment paradigm for patients with
Crohn's disease (CD), treatment efficacy is limited by primary and secondary non-response …

The use of mesenchymal stem cells has resulted in a breakthrough for the treatment of
complex perianal fistulas in Crohn's disease. This novel treatment is associated with a …

Background Perianal fistulas (PF) affect one-third patients with Crohn's disease (CD) with
limited therapeutic options. There is dearth of literature on safety and efficacy of bone …