Ageing, which can be defined as functional decline of an organism with time, is a major
factor of susceptibility to various chronic diseases, which constitute a huge burden for health …

Intercellular communication refers to the different ways through which cells communicate
with each other and transfer a variety of messages. These communication methods involve a …

Aging is expressed as a deterioration and frailty of various tissues, accompanied by
dysregulation of the pathways essential for homeostasis, resilience, and maintenance …

Gap junctions, comprising connexin proteins, create conduits directly coupling the
cytoplasms of adjacent cells. Expressed in essentially all tissues, dynamic gap junction …

Advances in public health have nearly doubled life expectancy over the last century, but this
demographic shift has also changed the landscape of human illness. Today, chronic and …

Our cells are comprised of billions of proteins, lipids, and other small molecules packed into
their respective subcellular organelles, with the daunting task of maintaining cellular …

Aging process is a complicated process that involves deteriorated performance at multiple
levels from cellular dysfunction to organ degeneration. For many years research has been …

While many theories have been proposed for the aging process, and many debates on the
matter of aging and the diseases of aging being either the result of the same or independent …

Dysregulation of intercellular communication is a hallmark of aging. To better quantify and
explore changes in intercellular communication, we present scDiffCom and scAgeCom …

The aging process is considered a universal and inevitable process of physiological decline
associated with a greater vulnerability to disease and death. Efforts to understand aging …