SUMMARY The transcription factor Shavenbaby (Svb), the only member of the OvoL family
in Drosophila, controls the fate of various epithelial embryonic cells and adult stem cells …

Summary The transcription factor Shavenbaby (Svb), the only member of the OvoL family in
Drosophila, controls the fate of various epithelial embryonic cells and adult stem cells. Post …

Summary The transcription factor Shavenbaby (Svb), the only member of the OvoL family in
Drosophila, controls intestinal stem cell differentiation. Post-translational modification of Svb …

Signaling pathways are key regulators of adult stem cell homeostasis and underlying
mechanisms are often deregulated in cancers. Recent studies of epithelial tumors have …

The proportion of stem cells versus differentiated progeny is well balanced to maintain tissue
homeostasis, which in turn depends on the balance of the different signaling pathways …

Tissue homeostasis relies on rewiring of stem cell transcriptional programs into those of
differentiated cells. Here, we investigate changes in chromatin occurring in a bipotent adult …

Adult stem cells must continuously fine‐tune their behavior to regenerate damaged organs
and avoid tumors. While several signaling pathways are well known to regulate somatic …

The manipulation of cell identity by reprograming holds immense potential in regenerative
medicine, but is often limited by the inefficient acquisition of fully functional cells. This …

Chromatin remodeling accompanies differentiation, however, its role in self-renewal is less
well understood. We report that in Drosophila, the chromatin remodeler Kismet/CHD7/CHD8 …

A fundamental question in developmental biology is how distinct cell fates are established
and maintained through epigenetic mechanisms in multicellular organisms. Here, we report …