Diffusion MRI tractography is the only noninvasive method to measure the structural
connectome in humans. However, recent validation studies have revealed limitations of …

Interest in structural brain connectivity has grown with the understanding that abnormal
neural connections may play a role in neurologic and psychiatric diseases. Small animal …

Rationale Disruptions of brain anatomical connectivity are believed to play a central role in
several neurological and psychiatric illnesses. The structural brain connectome is typically …

Diffusion MRI‐based tractography is the most commonly‐used technique when inferring the
structural brain connectome, ie, the comprehensive map of the connections in the brain. The …

Interregional connections of the brain measured with diffusion tractography can be used to
infer valuable information regarding both brain structure and function. However, different …

Diffusion MRI streamlines tractography has become a major technique for inferring structural
networks through reconstruction of brain connectome. However, quantification of structural …

Tractography is a powerful technique capable of non-invasively reconstructing the structural
connections in the brain using diffusion MRI images, but the validation of tractograms is …

Network neuroscience leverages diffusion-weighted magnetic resonance imaging and
tractography to quantify structural connectivity of the human brain. However, scientists and …

Neuroanatomical tract tracing methods are fundamental in providing" gold standard"
estimates of brain connectivity. However, tracer methods cannot be performed in humans …

Tractography based on non-invasive diffusion imaging is central to the study of human brain
connectivity. To date, the approach has not been systematically validated in ground truth …