Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis

J Heo, BJ Noh, S Lee, HY Lee, YH Kim… - EMBO molecular …, 2020 - embopress.org
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic
dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms …

Genetics and epigenetics of the multifunctional protein CTCF

GN Filippova - Current topics in developmental biology, 2007 - Elsevier
Recent advances in studying long‐range chromatin interactions have shifted focus from the
transcriptional regulation by nearby regulatory elements to recognition of the role of higher …

Functional analysis of CP2-like domain and SAM-like domain in TFCP2L1, novel pluripotency factor of embryonic stem cells

CM Kim, T Jang, HH Park - Applied biochemistry and biotechnology, 2016 - Springer
TFCP2L1 is a transcription factor that facilitates establishment and maintenance of
pluripotency in embryonic stem cells by forming a complex transcriptional network with other …

[HTML][HTML] CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features

K Essien, S Vigneau, S Apreleva, LN Singh… - Genome biology, 2009 - Springer
Background CTCF (CCCTC-binding factor) is an evolutionarily conserved zinc finger protein
involved in diverse functions ranging from negative regulation of MYC, to chromatin …

Transcription cofactor PC 4 plays essential roles in collaboration with the small subunit of general transcription factor TFIIE

Y Akimoto, S Yamamoto, S Iida, Y Hirose… - Genes to …, 2014 - Wiley Online Library
In eukaryotes, positive cofactor 4 (PC4) stimulates activator‐dependent transcription by
facilitating transcription initiation and the transition from initiation to elongation. It also forms …

Choice of binding sites for CTCFL compared to CTCF is driven by chromatin and by sequence preference

P Bergmaier, O Weth, S Dienstbach… - Nucleic acids …, 2018 - academic.oup.com
The two paralogous zinc finger factors CTCF and CTCFL differ in expression such that CTCF
is ubiquitously expressed, whereas CTCFL is found during spermatogenesis and in some …

[HTML][HTML] Key roles of CCCTC-binding factor in cancer evolution and development

Z Li, X Zhou, S Cai, J Fan, Z Wei, Y Chen… - Exploration of …, 2021 - explorationpub.com
The processes of cancer and embryonic development have a partially overlapping effect.
Several transcription factor families, which are highly conserved in the evolutionary history of …

[HTML][HTML] A regulatory role for the unstructured C-terminal domain of the CtBP transcriptional corepressor

AM Raicu, M Suresh, DN Arnosti - Journal of Biological Chemistry, 2024 - ASBMB
The C-terminal binding protein (CtBP) is a transcriptional corepressor that plays critical roles
in development, tumorigenesis, and cell fate. CtBP proteins are structurally similar to alpha …

[引用][C] The study on the role of chromatin architectural protein CTCF in the control of gene expression by establishing acute CTCF depletion system in human …

강무구 - 2021 - 연세대학교

[引用][C] Development of a Model System to Evaluate the Effects of CTCF on Global Transcriptional Patterns during Cell Differentiation

Y Flores, A Agostini, K Kirk, K Casey, B Davy… - Journal of Biological …, 2023 - Elsevier