The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Chronic lung disease is a leading cause of morbidity and mortality in the United States.
Quantitative techniques for assessing emphysema and related airway disease have been …

The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by
airflow limitation but also by factors such as exercise capacity and body mass index. Recent …

The fundamental importance of calibration for any measuring device is indisputable, but
computed tomography (CT) calibration in longitudinal lung densitometry studies is largely …

Background The mechanisms underlying airflow obstruction in COPD cannot be
distinguished by standard spirometry. We ascertain whether mathematical modeling of …

Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …

Purpose To prospectively investigate the effect of submaximal inspiration on computed
tomographic (CT) indexes used to quantify emphysema and to discriminate between effects …

Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and
mortality worldwide and results in substantial social and economic burdens. COPD is a …

Objectives A combination of functional measurements reflecting a decrease in maximum
flow, a degree of lung hyperinflation, the relationship between maximum inspiratory and …

Background Objective quantification of emphysema using computerized tomography (CT)
density measurements is rapidly gaining wide acceptance as an in vivo measurement tool …