Background Phenotypic characterization of patients with COPD may have potential
prognostic and therapeutic implications. Available information on the relationship between …

Rationale and Objectives Many patients with chronic obstructive pulmonary disease (COPD)
have marked discordance between forced expiratory volume in 1 second (FEV 1) and …

Background: Both emphysematous destruction of lung parenchyma and airway remodeling
is thought to contribute to airflow limitation in cases of chronic obstructive pulmonary disease …

In subjects with chronic obstructive pulmonary disease (COPD) computed tomographic (CT)
lung density correlates with direct pathological measurements of the size of the distal …

Quantitative computed tomography (QCT) can provide reliable and valid measures of lung
structure and volumes. Similar to lung function measured by spirometry, lung measures …

Background Existing CT emphysema measurements quantify the extent or clustering of
emphysema voxels in chronic obstructive pulmonary disease (COPD); however, these …

Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow
obstruction caused by emphysema or airway narrowing, or both. Low attenuation areas …

The development of the high-resolution computed tomography (HRCT) has improved the
ability to detect and quantify emphysema in various groups of patients with chronic airflow …

In the last decade, several studies have suggested the possible role of computed
tomography (CT) in the detection and the quantification of pulmonary emphysema. In order …

Purpose: To prospectively compare pulmonary function tests and helical computed
tomographic (CT) indexes for quantifying pulmonary emphysema with macroscopic and …