Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation, caused by emphysema and small airways disease (SAD). Computed tomography …

Emphysema is a major constituent of lung pathology in chronic obstructive pulmonary
disease, and emphysema is characterized by loss of lung tissue. Computed tomography …

Background More accurate phenotyping of COPD is of great interest since it may have
prognostic and therapeutic consequences. We attempted to explore the possible …

Emphysema distribution is associated with chronic obstructive pulmonary disease. It is,
however, unknown whether computed tomography (CT)-quantified emphysema distribution …

ABSTRACT COPD is a heterogeneous disorder with clinical assessment becoming
increasingly multidimensional. We hypothesized HRCT phenotype would strongly influence …

Abstract Saitoh T, Koba H, Shijubo N, Tanaka H, Sugaya F. Lobar distribution of emphysema
in computed tomographic densitometric analysis. Invest Radiol 2000; 35: 235–243 …

Purpose To test the hypothesis—given the increasing emphasis on quantitative computed
tomographic (CT) phenotypes of chronic obstructive pulmonary disease (COPD)—that a …

Background Chronic obstructive pulmonary disease (COPD) has variable subtypes
involving mixture of large airway inflammation, small airway disease, and emphysema. This …

Rationale: The rate of decline of lung function is greater than age-related change in a
substantial proportion of patients with chronic obstructive pulmonary disease, even after …

Novel therapeutic options in chronic obstructive pulmonary disease (COPD) require delicate
patient selection and thus demand for expert radiologists visually and quantitatively …