AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to
an infective insult. This process often leads to widespread tissue injury and multiple organ …

Sepsis is a serious medical condition that can lead to multi-organ failure and shock, and it is
associated with increased mortality. Acute kidney injury (AKI) is a frequent complication of …

Acute kidney injury (AKI) is a common sequel of sepsis in the intensive care unit. It is being
suggested that sepsis-induced AKI may have a distinct pathophysiology and identity …

Acute kidney injury (AKI) is a serious condition that affects many ICU patients. The most
common causes of AKI in ICU are severe sepsis and septic shock. The mortality of AKI in …

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Severe sepsis is the trigger for the development of approximately 50% of cases of acute
kidney injury (AKI) among critically ill patients. 1 Even in patients with less severe infections …

Sepsis is a severe and dysregulated inflammatory response to infection characterized by
end-organ dysfunction distant from the primary site of infection. Development of acute kidney …

Traditionally, renal ischemia has been regarded as central to the pathogenesis of sepsis-
associated acute kidney injury (SA-AKI). Accordingly, hemodynamic management of SA-AKI …