The modification of milk protein composition through transgenesis: progress and problems

JC Mercier, JL Vilotte - Transgenic Animals, 2022 - taylorfrancis.com
Significant modifications of milk composition have been achieved by the successful high
expression of several milk protein-encoding transgenes in animals, mainly mice. Potential …

[PDF][PDF] Changing the composition and properties of milk

JD Murray, EA Maga - Transgenic animals in agriculture, 1999 - higiene.unex.es
Since the advent of the molecular biology era in the early 1970s, biotechnology has held
great promise for improving animal agriculture. Since 1982, genetic engineering has held …

Application of transgenesis to modifying milk protein composition.

JL Vilotte, S Soulier, MA Persuy, L Lepourry, S Legrain… - 1997 - cabidigitallibrary.org
Methodologies used in the production of transgenic animals, studies on the expression of
milk protein transgenes, and steps involved in the use of the mammary gland as a bioreactor …

Production of proteins in the milk of transgenic livestock: problems, solutions, and successes

A Colman - The American journal of clinical nutrition, 1996 - Elsevier
The milk of livestock can be modified dramatically by introducing foreign DNA into the
germline. Exclusive expression of this DNA is ensured by the presence of regulatory …

[引用][C] Transgenic animals:“Great and small”

WN Drohan - Journal of cellular biochemistry, 1992 - Wiley Online Library
Technology is currently available to create transgenic livestock animals, opening up the
possibility for their commercial use. One obvious direction this technology could take is to …

Genetic engineering of milk composition: modification of milk components in lactating transgenic animals

HC Yom, RD Bremel - The American journal of clinical nutrition, 1993 - Elsevier
Recent progress in recombinant DNA technology as well as in embryo manipulation and
transfer has made the introduction of specific genes into the germline of animals relatively …

Preparation of recombinant proteins in milk

LM Houdebine - Recombinant Gene Expression: Reviews and …, 2004 - Springer
Using transgenic animals as the source of recombinant proteins has several specific
advantages. Large amounts of proteins can be obtained, essentially from milk. These …

Transgenesis for the study and the control of lactation

LM Houdebine, S Rival, T Pantano… - Reproduction …, 2002 - rnd.edpsciences.org
The study and the control of milk synthesis are required to decipher the mechanisms of gene
expression, to improve milk production, to modify milk composition, to induce a resistance to …

Preparation of recombinant proteins in milk to improve human and animal health

E Soler, D Thépot, S Rival-Gervier… - Reproduction …, 2006 - rnd.edpsciences.org
Milk is a very abundant source of proteins for animal and human consumption. Milk
composition can be modified using transgenesis, including exogenous gene addition and …

Prospects for the genetic engineering of milk

AJ Clark - Journal of cellular biochemistry, 1992 - Wiley Online Library
Milk and milk products comprise a substantial fraction of the protein intake of the
industrialised West. The establishment of germline manipulation techniques in cows offers …