Effect of anlotinib as a third‐or further‐line therapy in advanced non‐small cell lung cancer patients with different histologic types: subgroup analysis in the …

Y Cheng, B Han, K Li, Q Wang, L Zhang, J Shi… - Cancer …, 2020 - Wiley Online Library
Background Anlotinib showed significant survival benefits in advanced non‐small cell lung
cancer (NSCLC) patients as a third‐or further‐line treatment in the ALTER0303 trial. We …

Efficacy and safety of third-line treatment with anlotinib in patients with refractory advanced non-small-cell lung cancer (ALTER-0303): a randomised, double-blind …

B Han, K Li, Q Wang, Y Zhao, L Zhang, J Shi… - The Lancet …, 2017 - thelancet.com
Background Anlotinib hydrochloride, an oral tyrosine kinase inhibitor targeting VEGFR,
FGFR, PDGFR, and c-kit, showed promising efficacy in a phase 2 study. Here, we evaluated …

[HTML][HTML] Efficacy and safety of anlotinib in patients with advanced non-small cell lung cancer

Y Zhong, Q Wei, Y Lu, X Tang, Z Wang… - Journal of thoracic …, 2020 - ncbi.nlm.nih.gov
Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer
and its incidence seriously affects human health. The purpose of this study was to evaluate …

Update on real-world efficacy of anlotinib in non-small cell lung cancer.

J Gao, Y Xu, Y Liu, L Liang, Y Yu, D Zhao, J Jin… - 2023 - ascopubs.org
e21173 Background: Anlotinib is a novel oral small molecule TKI with anti-tumor vascular
generation and growth inhibition effects, targeting VEGFR, PDGFR, FGFR, and c-kit. It has …

1119P Real-world efficacy and safety of anlotinib in combination with PD-1/PD-L1 inhibitors as first-line or second-line treatment in advanced non-small cell lung …

Q Wang, C Ma, T Wang, G Chen, H Wang… - Annals of …, 2022 - annalsofoncology.org
Background Antiangiogenic therapy combined with PD-1/PD-L1 inhibitors has shown
excellent efficacy in advanced NSCLC pts. The ALTER 0303 trial showed that anlotinib …

Anlotinib as a third-line therapy in patients with refractory advanced non-small-cell lung cancer: a multicentre, randomised phase II trial (ALTER0302)

B Han, K Li, Y Zhao, B Li, Y Cheng, J Zhou, Y Lu… - British journal of …, 2018 - nature.com
Background: Anlotinib (AL3818) is a novel multitarget tyrosine kinase inhibitor, inhibiting
tumour angiogenesis and proliferative signalling. The objective of this study was to assess …

The real-world efficacy and safety of anlotinib in advanced non-small cell lung cancer

F Wang, F Jin, B Cheng, Y Zhang, Q Zhou… - Journal of Cancer …, 2022 - Springer
Purpose Anlotinib is an anti-angiogenetic multi-targeted tyrosine kinase inhibitor. This study
aimed to evaluate the efficacy and safety of anlotinib in advanced non-small cell lung cancer …

Efficacy and safety of anlotinib in 16 patients with advanced non-small cell lung cancer

XY Si, HP Wang, XT Zhang, MZ Wang… - Zhonghua nei ke za …, 2018 - europepmc.org
Objective: To evaluate the efficacy and safety of anlotinib in patients with advanced non-
small cell lung cancer (NSCLC). Methods: Patients with stage ⅢB/Ⅳ NSCLC who …

324P Efficacy and safety analysis of anlotinib combined with immunotherapy as second-line therapy for advanced non-small cell lung cancer (NSCLC)

Q Shi, Q Xie, H Lin, Y He, X Zheng… - Annals of …, 2022 - annalsofoncology.org
Background No standard treatment exists for non-small cell lung cancer (NSCLC) with
failure of first-line therapies. Combination of antiangiogenic therapy and immune checkpoint …

P2. 03a-001 A Randomized Phase III Clinical Trial of Anlotinib Hydrochloride in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC): Topic: Clinical Trials

B Han, K Li, Y Zhao, Q Wang, L Zhang, J Shi… - Journal of Thoracic …, 2017 - jto.org
Background Anlotinib hydrochloride, a novel multi-targeted tyrosine kinase inhibitor (TKI)
was found to exhibit excellent inhibitory efficiency on a variety of receptor tyrosine kinases …